Curation Details
Interaction ID: IM-29535-243

Unique identifier for interactor Auniprotkb:P38398
Unique identifier for interactor Buniprotkb:Q96SB3
Alternative identifier for interactor Aintact:EBI-349905
uniprotkb:Q3LRJ0
uniprotkb:O15129
uniprotkb:Q7KYU9
ensembl:ENSP00000350283.3
ensembl:ENSP00000419103.2
ensembl:ENSP00000419274.2
ensembl:ENSP00000478114.2
uniprotkb:Q3LRJ6
uniprotkb:Q6IN79
uniprotkb:Q1RMC1
uniprotkb:E9PFZ0
Alternative identifier for interactor Bintact:EBI-351275
uniprotkb:Q8TCR9
intact:EBI-28984643
ensembl:ENSP00000478767.1
intact:EBI-4401886
uniprotkb:D3DTX6
Aliases for Apsi-mi:brca1_human(display_long)
uniprotkb:BRCA1(gene name)
psi-mi:BRCA1(display_short)
uniprotkb:RNF53(gene name synonym)
uniprotkb:RING finger protein 53(gene name synonym)
uniprotkb:RING-type E3 ubiquitin transferase BRCA1(gene name synonym)
Aliases for Bpsi-mi:neb2_human(display_long)
uniprotkb:Neurabin-II(gene name synonym)
uniprotkb:Spinophilin(gene name synonym)
uniprotkb:Protein phosphatase 1 regulatory subunit 9B(gene name synonym)
uniprotkb:PPP1R9B(gene name)
psi-mi:PPP1R9B(display_short)
uniprotkb:PPP1R6(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorKim et al. (2021)
Identifier of the publicationpubmed:34591612
imex:IM-29535
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-34582905
imex:IM-29535-243
Confidence scoreintact-miscore:0.50
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F5B
curation depth:imex curation
dataset:Cancer - Interactions investigated in the context of cancer
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-mda_mb_231)
taxid:9606(Homo sapiens MDA-MB-231 breast adenocarcinoma cell)
Parameters of the interaction-
Creation date2022/06/24
Update date2024/09/03
negative Boolean valuefalse
Feature(s) for interactor Aflag tag:n-n
Feature(s) for interactor Bha tag:n-n
mutation decreasing interaction:212-212
mutation increasing interaction:248-248
mutation disrupting interaction:635-635
mutation increasing interaction:451-451
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot