Curation Details
Interaction ID: IM-29535-221

Unique identifier for interactor Auniprotkb:P31749
Unique identifier for interactor Buniprotkb:Q16543
Alternative identifier for interactor Aintact:EBI-296087
uniprotkb:Q9BWB6
uniprotkb:B2RAM5
ensembl:ENSP00000270202.4
ensembl:ENSP00000384293.2
ensembl:ENSP00000385326.2
ensembl:ENSP00000450688.1
ensembl:ENSP00000451166.1
ensembl:ENSP00000451828.1
ensembl:ENSP00000497822.1
ensembl:ENSP00000507879.1
uniprotkb:B7Z5R1
Alternative identifier for interactor Bintact:EBI-295634
uniprotkb:Q53YA2
ensembl:ENSP00000222005.1
intact:EBI-21355356
Aliases for Apsi-mi:akt1_human(display_long)
uniprotkb:AKT1(gene name)
psi-mi:AKT1(display_short)
uniprotkb:PKB(gene name synonym)
uniprotkb:RAC(gene name synonym)
uniprotkb:RAC-PK-alpha(gene name synonym)
uniprotkb:Protein kinase B(gene name synonym)
uniprotkb:Proto-oncogene c-Akt(gene name synonym)
uniprotkb:Protein kinase B alpha(gene name synonym)
Aliases for Bpsi-mi:cdc37_human(display_long)
uniprotkb:CDC37(gene name)
psi-mi:CDC37(display_short)
uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)
uniprotkb:p50Cdc37(gene name synonym)
uniprotkb:CDC37A(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorKim et al. (2021)
Identifier of the publicationpubmed:34591612
imex:IM-29535
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-34581687
imex:IM-29535-221
Confidence scoreintact-miscore:0.71
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST3 ST4 F1
curation depth:imex curation
dataset:Cancer - Interactions investigated in the context of cancer
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-mda_mb_231)
taxid:9606(Homo sapiens MDA-MB-231 breast adenocarcinoma cell)
Parameters of the interaction-
Creation date2022/06/24
Update date2024/08/11
negative Boolean valuefalse
Feature(s) for interactor Amutation:17-17
flag tag:c-c
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AIdentification by mass spectrometry
Participant identification method for interactor BIdentification by mass spectrometry