Curation Details
Interaction ID: IM-29513-6

Unique identifier for interactor Auniprotkb:P16104
Unique identifier for interactor Buniprotkb:Q9NVI1
Alternative identifier for interactor Aintact:EBI-494830
uniprotkb:Q4ZGJ7
uniprotkb:Q6IAS5
ensembl:ENSP00000364310.1
ensembl:ENSP00000434024.1
Alternative identifier for interactor Bintact:EBI-1013291
uniprotkb:A4ZVE4
ensembl:ENSP00000310842.8
ensembl:ENSP00000512832.1
uniprotkb:Q96JN1
uniprotkb:Q96ST0
uniprotkb:Q9BT96
uniprotkb:A5YMH4
uniprotkb:A6NJZ0
Aliases for Apsi-mi:h2ax_human(display_long)
uniprotkb:H2AX(gene name)
psi-mi:H2AX(display_short)
uniprotkb:H2AFX(gene name synonym)
uniprotkb:Histone H2A.X(gene name synonym)
Aliases for Bpsi-mi:fanci_human(display_long)
uniprotkb:FANCI(gene name)
psi-mi:FANCI(display_short)
uniprotkb:KIAA1794(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorHu et al. (2018)
Identifier of the publicationimex:IM-29513
pubmed:31240132
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-34615301
imex:IM-29513-6
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f2f
comment:"\"Immunoprecipitation of FANCI in 293FT cells with knocked down expression of CTDP1 leads to a decrease in the FANCI interaction with the DNA damage foci marker γ-H2AX following treatment with cisplatin (Fig. 2f).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293ft)
taxid:9606(Homo sapiens HEK293FT embryonic kidney cell)
Parameters of the interaction-
Creation date2021/05/18
Update date2022/09/23
negative Boolean valuefalse
Feature(s) for interactor Aphosphorylated residue:139-139
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot