Curation Details
Interaction ID: IM-29512-11

Unique identifier for interactor Auniprotkb:Q06787
Unique identifier for interactor Buniprotkb:Q13283
Alternative identifier for interactor Aintact:EBI-366305
uniprotkb:A6NNH4
uniprotkb:D3DWT0
uniprotkb:D3DWT1
uniprotkb:D3DWT2
uniprotkb:G8JL90
uniprotkb:Q5PQZ6
uniprotkb:Q16578
ensembl:ENSP00000359506.5
uniprotkb:Q99054
Alternative identifier for interactor Bintact:EBI-1047359
uniprotkb:Q5HYE9
ensembl:ENSP00000348578.3
ensembl:ENSP00000377681.3
ensembl:ENSP00000430480.2
ensembl:ENSP00000502880.1
ensembl:ENSP00000503039.1
ensembl:ENSP00000503699.1
ensembl:ENSP00000503939.1
ensembl:ENSP00000504140.1
ensembl:ENSP00000504627.1
intact:EBI-1384154
Aliases for Apsi-mi:fmr1_human(display_long)
uniprotkb:FMR1(gene name)
psi-mi:FMR1(display_short)
uniprotkb:Fragile X messenger ribonucleoprotein(gene name synonym)
uniprotkb:Protein FMR-1(gene name synonym)
Aliases for Bpsi-mi:g3bp1_human(display_long)
uniprotkb:G3BP1(gene name)
psi-mi:G3BP1(display_short)
uniprotkb:G3BP(gene name synonym)
uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)
uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorTaha et al. (2021)
Identifier of the publicationimex:IM-29512
pubmed:32525608
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-34573820
imex:IM-29512-11
Confidence scoreintact-miscore:0.58
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F4C
comment:"\"As depicted in Fig. 4C, G3BP1 full-length (FL) and the fragment M3, but not M1, M2, or M4, bound to FMRPN-term, indicating that the proline-rich region (PXXP) of G3BP1, which is located between the acidic region and the RRM/RGG, may be involved in interaction with FMRPN-term.\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2022/03/11
Update date2022/06/04
negative Boolean valuefalse
Feature(s) for interactor Aglutathione s tranferase tag:?-?
sufficient binding region:1-218
Feature(s) for interactor Bflag tag:n-n
necessary binding region:222-338
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot