| Unique identifier for interactor A | uniprotkb:P06493 |
| Unique identifier for interactor B | uniprotkb:P46527 |
| Alternative identifier for interactor A | intact:EBI-444308 uniprotkb:O60764 uniprotkb:C9J497 uniprotkb:A8K7C4 ensembl:ENSP00000378699.3 |
| Alternative identifier for interactor B | intact:EBI-519280 uniprotkb:Q16307 uniprotkb:Q9BUS6 ensembl:ENSP00000228872.4 ensembl:ENSP00000507272.1 uniprotkb:Q5U0H2 |
| Aliases for A | psi-mi:cdk1_human(display_long) uniprotkb:p34 protein kinase(gene name synonym) uniprotkb:Cell division protein kinase 1(gene name synonym) uniprotkb:CDK1(gene name) psi-mi:CDK1(display_short) uniprotkb:CDC2(gene name synonym) uniprotkb:Cell division control protein 2 homolog(gene name synonym) uniprotkb:CDC28A(gene name synonym) uniprotkb:CDKN1(gene name synonym) uniprotkb:P34CDC2(gene name synonym) |
| Aliases for B | psi-mi:cdn1b_human(display_long) uniprotkb:Cyclin-dependent kinase inhibitor p27(gene name synonym) uniprotkb:p27Kip1(gene name synonym) uniprotkb:CDKN1B(gene name) psi-mi:CDKN1B(display_short) uniprotkb:KIP1(gene name synonym) uniprotkb:p27(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Kabuta et al. (2013) |
| Identifier of the publication | imex:IM-29336 pubmed:23543736 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-28996916 imex:IM-29336-42 |
| Confidence score | intact-miscore:0.89 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:SF3E comment:"\"We also tested whether UCH-L1 competes with the CDK inhibitors p27 (Kip1) or p21 (Cip1) for binding to CDKs. UCH-L1 did not affect the level of interaction between CDK1 and p21, CDK1 and p27, CDK4 and p21, and CDK4 and p27 (supplemental Fig. S3, D and E), indicating that UCH-L1 does not compete with p27 or p21 for the binding to CDKs.\"" curation depth:imex curation dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases. dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9534(chlae-cos_7) taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) |
| Parameters of the interaction | - |
| Creation date | 2021/09/30 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | flag tag:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |