Curation Details
Interaction ID: IM-29336-37

Unique identifier for interactor Auniprotkb:P09936
Unique identifier for interactor Buniprotkb:Q00535
Alternative identifier for interactor Aintact:EBI-714860
uniprotkb:Q71UM0
intact:EBI-1049220
uniprotkb:Q4W5K6
ensembl:ENSP00000284440.4
ensembl:ENSP00000422542.1
Alternative identifier for interactor Bintact:EBI-1041567
uniprotkb:A1XKG3
ensembl:ENSP00000419782.1
Aliases for Apsi-mi:uchl1_human(display_long)
uniprotkb:Ubiquitin thioesterase L1(gene name synonym)
uniprotkb:Neuron cytoplasmic protein 9.5(gene name synonym)
uniprotkb:PGP 9.5(gene name synonym)
uniprotkb:UCHL1(gene name)
psi-mi:UCHL1(display_short)
Aliases for Bpsi-mi:cdk5_human(display_long)
uniprotkb:CDK5(gene name)
psi-mi:CDK5(display_short)
uniprotkb:Cell division protein kinase 5(gene name synonym)
uniprotkb:Tau protein kinase II catalytic subunit(gene name synonym)
uniprotkb:Serine/threonine-protein kinase PSSALRE(gene name synonym)
uniprotkb:CDKN5(gene name synonym)
uniprotkb:Cyclin-dependent-like kinase 5(gene name synonym)
uniprotkb:PSSALRE(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorKabuta et al. (2013)
Identifier of the publicationimex:IM-29336
pubmed:23543736
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-27122106
imex:IM-29336-37
Confidence scoreintact-miscore:0.50
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:SF8
comment:"\"We confirmed that CDK5D144N interacted with UCH-L1 at a level comparable with that with CDK5WT (supplemental Fig. S8).\""
curation depth:imex curation
dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.
dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2021/09/30
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bflag tag:?-?
mutation with no effect:144-144
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot