Curation Details
Interaction ID: IM-29336-33

Unique identifier for interactor Auniprotkb:Q00535
Unique identifier for interactor Buniprotkb:Q15078
Alternative identifier for interactor Aintact:EBI-1041567
uniprotkb:A1XKG3
ensembl:ENSP00000419782.1
Alternative identifier for interactor Bintact:EBI-746189
uniprotkb:Q5U0G3
uniprotkb:E1P664
ensembl:ENSP00000318486.3
Aliases for Apsi-mi:cdk5_human(display_long)
uniprotkb:CDK5(gene name)
psi-mi:CDK5(display_short)
uniprotkb:Cell division protein kinase 5(gene name synonym)
uniprotkb:Tau protein kinase II catalytic subunit(gene name synonym)
uniprotkb:Serine/threonine-protein kinase PSSALRE(gene name synonym)
uniprotkb:CDKN5(gene name synonym)
uniprotkb:Cyclin-dependent-like kinase 5(gene name synonym)
uniprotkb:PSSALRE(gene name synonym)
Aliases for Bpsi-mi:cd5r1_human(display_long)
uniprotkb:Cyclin-dependent kinase 5 regulatory subunit 1(gene name synonym)
uniprotkb:TPKII regulatory subunit(gene name synonym)
uniprotkb:CDK5R1(gene name)
psi-mi:CDK5R1(display_short)
uniprotkb:CDK5R(gene name synonym)
uniprotkb:NCK5A(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorKabuta et al. (2013)
Identifier of the publicationimex:IM-29336
pubmed:23543736
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-27122078
imex:IM-29336-33
Confidence scoreintact-miscore:0.94
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:SF3B
comment:"\"Coimmunoprecipitation assays showed that UCH-L1 does not affect interaction levels between CDK4 and cyclin D, CDK5 and p35, and CDK1 and cyclin B (supplemental Fig. S3, A–C).\""
curation depth:imex curation
dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.
dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9534(chlae-cos_7)
taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)
Parameters of the interaction-
Creation date2021/09/30
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Aflag tag:?-?
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot