Curation Details
Interaction ID: IM-29336-15

Unique identifier for interactor Auniprotkb:P24385
Unique identifier for interactor Buniprotkb:P11802
Alternative identifier for interactor Aintact:EBI-375001
uniprotkb:Q6LEF0
ensembl:ENSP00000227507.2
Alternative identifier for interactor Bintact:EBI-295644
uniprotkb:O00576
uniprotkb:Q6FG61
uniprotkb:B4DNF9
uniprotkb:B2R9A0
ensembl:ENSP00000257904.5
Aliases for Apsi-mi:ccnd1_human(display_long)
uniprotkb:CCND1(gene name)
psi-mi:CCND1(display_short)
uniprotkb:BCL1(gene name synonym)
uniprotkb:PRAD1(gene name synonym)
uniprotkb:PRAD1 oncogene(gene name synonym)
uniprotkb:BCL-1 oncogene(gene name synonym)
uniprotkb:B-cell lymphoma 1 protein(gene name synonym)
Aliases for Bpsi-mi:cdk4_human(display_long)
uniprotkb:CDK4(gene name)
psi-mi:CDK4(display_short)
uniprotkb:Cell division protein kinase 4(gene name synonym)
uniprotkb:PSK-J3(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorKabuta et al. (2013)
Identifier of the publicationimex:IM-29336
pubmed:23543736
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-27122067
imex:IM-29336-15
Confidence scoreintact-miscore:0.98
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:SF3A
comment:"\"Coimmunoprecipitation assays showed that UCH-L1 does not affect interaction levels between CDK4 and cyclin D, CDK5 and p35, and CDK1 and cyclin B (supplemental Fig. S3, A–C).\""
curation depth:imex curation
dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.
dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9534(chlae-cos_7)
taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)
Parameters of the interaction-
Creation date2021/09/30
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bflag tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot