| Unique identifier for interactor A | uniprotkb:P16056 |
| Unique identifier for interactor B | uniprotkb:Q01097 |
| Alternative identifier for interactor A | intact:EBI-1798780 uniprotkb:Q62125 |
| Alternative identifier for interactor B | intact:EBI-400125 uniprotkb:Q9DCB2 |
| Aliases for A | psi-mi:met_mouse(display_long) uniprotkb:Met(gene name) psi-mi:Met(display_short) uniprotkb:Scatter factor receptor(gene name synonym) uniprotkb:HGF/SF receptor(gene name synonym) uniprotkb:Tyrosine-protein kinase Met(gene name synonym) uniprotkb:Proto-oncogene c-Met(gene name synonym) |
| Aliases for B | psi-mi:nmde2_mouse(display_long) uniprotkb:Glutamate [NMDA] receptor subunit epsilon-2(gene name synonym) uniprotkb:Grin2b(gene name) psi-mi:Grin2b(display_short) uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0813"(proximity ligation assay) |
| First author | Xie et al. (2016) |
| Identifier of the publication | imex:IM-29320 pubmed:27086544 |
| NCBI Taxonomy identifier for interactor A | taxid:10090(mouse) taxid:10090(Mus musculus) |
| NCBI Taxonomy identifier for interactor B | taxid:10090(mouse) taxid:10090(Mus musculus) |
| Interaction types | psi-mi:"MI:2364"(proximity) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-27118478 imex:IM-29320-17 |
| Confidence score | intact-miscore:0.27 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F3D comment:"\"there is a dynamic regulation of these interactions when MET is activated by HGF stimulation for 5, 10 or 30 minutes (Fig. 3F–3J). Three distinct interaction states were observed: 1) no change in the interaction following addition of the ligand (MET and NTRK3, MET and SHANK3, Fig. 3F and and3H),3H), 2) a statistically significant decrease in the interaction following HGF addition (MET and SYNGAP1, Fig. 3G), and 3) a statistically significant increase in the interaction following HGF addition (MET and GRIN2B, MET and GRM5, Fig. 3I–3J).\"" curation depth:imex curation dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:10090(mouse-brain-cortex) taxid:10090(Mus musculus brain cortex) |
| Parameters of the interaction | - |
| Creation date | 2021/10/27 |
| Update date | 2021/10/29 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Identification by antibody |
| Participant identification method for interactor B | Identification by antibody |