Curation Details
Interaction ID: IM-29293-1

Unique identifier for interactor Auniprotkb:Q9UIF7
Unique identifier for interactor Buniprotkb:P43246
Alternative identifier for interactor Aintact:EBI-725721
uniprotkb:Q15830
uniprotkb:Q9UBP2
uniprotkb:Q9UBS7
uniprotkb:Q9UIF4
uniprotkb:Q9UIF5
uniprotkb:Q9UIF6
uniprotkb:D3DPZ4
ensembl:ENSP00000361170.3
ensembl:ENSP00000500891.1
Alternative identifier for interactor Bintact:EBI-355888
uniprotkb:O75488
uniprotkb:B4E2Z2
ensembl:ENSP00000233146.2
Aliases for Apsi-mi:mutyh_human(display_long)
uniprotkb:MutY homolog(gene name synonym)
uniprotkb:MUTYH(gene name)
psi-mi:MUTYH(display_short)
uniprotkb:MYH(gene name synonym)
Aliases for Bpsi-mi:msh2_human(display_long)
uniprotkb:MSH2(gene name)
psi-mi:MSH2(display_short)
uniprotkb:MutS protein homolog 2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorBai et al. (2007)
Identifier of the publicationpubmed:17081686
imex:IM-29293
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-27104229
imex:IM-29293-1
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:Fig. 1
comment:"\"Physical interaction between hMutSα and hMYH(R231L). Purified hMutSα (hMSH2/hMSH6 complex, 460 ng) pulled down by GST-hMYH beads was fractionated by a 10% SDS-polyacrylamide gel followed by Western blot analysis using antibodies against hMSH2.\""
curation depth:imex curation
dataset:Cancer - Interactions investigated in the context of cancer
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2021/10/11
Update date2024/11/15
negative Boolean valuefalse
Feature(s) for interactor Aglutathione s tranferase tag:?-?
mutation with no effect:242-242
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot