Curation Details
Interaction ID: IM-29239-3

Unique identifier for interactor Auniprotkb:P37840
Unique identifier for interactor Buniprotkb:P00441
Alternative identifier for interactor Aintact:EBI-985879
uniprotkb:Q13701
uniprotkb:Q4JHI3
uniprotkb:Q6IAU6
uniprotkb:A8K2A4
ensembl:ENSP00000338345.3
ensembl:ENSP00000378437.1
ensembl:ENSP00000378442.4
ensembl:ENSP00000422238.1
ensembl:ENSP00000426955.1
ensembl:ENSP00000500990.1
Alternative identifier for interactor Bintact:EBI-990792
ensembl:ENSP00000270142.7
uniprotkb:A6NHJ0
uniprotkb:Q16669
uniprotkb:Q16711
uniprotkb:Q16838
uniprotkb:Q16839
uniprotkb:Q16840
uniprotkb:Q6NR85
uniprotkb:D3DSE4
Aliases for Apsi-mi:syua_human(display_long)
uniprotkb:Non-A beta component of AD amyloid(gene name synonym)
uniprotkb:Non-A4 component of amyloid precursor(gene name synonym)
uniprotkb:SNCA(gene name)
psi-mi:SNCA(display_short)
uniprotkb:NACP(gene name synonym)
uniprotkb:PARK1(gene name synonym)
Aliases for Bpsi-mi:sodc_human(display_long)
uniprotkb:Superoxide dismutase 1(gene name synonym)
uniprotkb:SOD1(gene name)
psi-mi:SOD1(display_short)
Interaction detection methodspsi-mi:"MI:1203"(split luciferase complementation)
First authorHelferich et al. (2015)
Identifier of the publicationpubmed:26643113
imex:IM-29239
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-27092138
imex:IM-29239-3
Confidence scoreintact-miscore:0.57
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 1a,b add. file 2 fig.4a,b
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:Brain Disease - Neurological Diseases & Disorders
dataset:Parkinsons - Interactions investigated in the context of Parkinsons disease
dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.
NCBI Taxonomy identifier for the host organismtaxid:9606(human-h4)
taxid:9606(Homo sapiens H4 neurogioma cell)
Parameters of the interaction-
Creation date2021/09/21
Update date2024/07/30
negative Boolean valuefalse
Feature(s) for interactor Amutation decreasing interaction:30-30
mutation decreasing interaction:53-53
gaussia-c:c-c
Feature(s) for interactor Bgaussia-n:c-c
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ATag visualisation by luciferase assay
Participant identification method for interactor BTag visualisation by luciferase assay