Curation Details
Interaction ID: IM-29230-1

Unique identifier for interactor Auniprotkb:Q7KU24
Unique identifier for interactor Buniprotkb:Q13148
Alternative identifier for interactor Aintact:EBI-3403984
uniprotkb:Q24376
uniprotkb:Q9VQJ9
Alternative identifier for interactor Bintact:EBI-372899
intact:EBI-2821405
uniprotkb:A4GUK4
uniprotkb:A4GUK5
uniprotkb:A4GUK6
uniprotkb:B2R629
uniprotkb:Q53H27
ensembl:ENSP00000240185.4
ensembl:ENSP00000491203.1
uniprotkb:B4DJ45
uniprotkb:Q6FI92
uniprotkb:E2PU12
uniprotkb:Q96DJ0
Aliases for Apsi-mi:chd1_drome(display_long)
uniprotkb:Chd1(gene name)
psi-mi:Chd1(display_short)
uniprotkb:ATP-dependent helicase Chd1(gene name synonym)
uniprotkb:CG3733(orf name)
Aliases for Bpsi-mi:tadbp_human(display_long)
uniprotkb:TARDBP(gene name)
psi-mi:TARDBP(display_short)
uniprotkb:TDP43(gene name synonym)
Interaction detection methodspsi-mi:"MI:0030"(cross-linking study)
First authorBerson et al. (2017)
Identifier of the publicationpubmed:29153328
imex:IM-29230
NCBI Taxonomy identifier for interactor Ataxid:7227(drome)
taxid:7227("Drosophila melanogaster (Fruit fly)")
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-27089178
imex:IM-29230-1
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig.5b
comment:"\"TDP-43 co-immunoprecipitated Chd1-HA primarily in the soluble fraction (Figure 5B), although TDP-43 was localized to both the soluble and chromatin fractions (Figure 5B).\""
dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:7227(drome)
taxid:7227("Drosophila melanogaster (Fruit fly)")
Parameters of the interaction-
Creation date2021/09/20
Update date2021/09/20
negative Boolean valuefalse
Feature(s) for interactor Aha tag:?-?
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot