Curation Details
Interaction ID: IM-29214-1

Unique identifier for interactor Auniprotkb:Q9UF33
Unique identifier for interactor Buniprotkb:Q04771
Alternative identifier for interactor Aintact:EBI-3950019
uniprotkb:D6RAL5
Alternative identifier for interactor Bintact:EBI-1383616
ensembl:ENSP00000263640.3
ensembl:ENSP00000387127.2
ensembl:ENSP00000387273.2
ensembl:ENSP00000400767.2
ensembl:ENSP00000405004.1
ensembl:ENSP00000440091.2
ensembl:ENSP00000500109.1
ensembl:ENSP00000500605.1
ensembl:ENSP00000507086.1
ensembl:ENSP00000507102.1
ensembl:ENSP00000507113.1
ensembl:ENSP00000507727.1
ensembl:ENSP00000507730.1
ensembl:ENSP00000508136.1
ensembl:ENSP00000508189.1
Aliases for Apsi-mi:epha6_human(display_long)
uniprotkb:HEK12(gene name synonym)
uniprotkb:EPH-like kinase 12(gene name synonym)
uniprotkb:EPHA6(gene name)
psi-mi:EPHA6(display_short)
uniprotkb:EHK2(gene name synonym)
uniprotkb:EPH homology kinase 2(gene name synonym)
Aliases for Bpsi-mi:acvr1_human(display_long)
uniprotkb:Activin receptor-like kinase 2(gene name synonym)
uniprotkb:TGF-B superfamily receptor type I(gene name synonym)
uniprotkb:ACVRLK2(gene name synonym)
uniprotkb:Activin receptor type I(gene name synonym)
uniprotkb:Serine/threonine-protein kinase receptor R1(gene name synonym)
uniprotkb:ACVR1(gene name)
psi-mi:ACVR1(display_short)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorRaja et al. (2019)
Identifier of the publicationimex:IM-29214
pubmed:31483918
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-27086122
imex:IM-29214-1
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:Fig. 4B,C
comment:Furthermore, binding of EPHA6 to the ALK‐2‐CA receptor was reduced in the presence of LDN193189
antagonist:LDN193189
curation depth:imex curation
dataset:Brain Disease - Neurological Diseases & Disorders
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-glioblastoma)
taxid:9606(Homo sapiens glioblastoma)
Parameters of the interaction-
Creation date2021/09/12
Update date2021/09/12
negative Boolean valuefalse
Feature(s) for interactor Aflag tag:c-c
Feature(s) for interactor Bha tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot