| Unique identifier for interactor A | uniprotkb:P10636 |
| Unique identifier for interactor B | uniprotkb:P49841 |
| Alternative identifier for interactor A | intact:EBI-366182 uniprotkb:Q1RMF6 uniprotkb:Q53YB1 uniprotkb:P18518 uniprotkb:Q14799 uniprotkb:Q15549 uniprotkb:Q15550 uniprotkb:Q15551 uniprotkb:Q5CZI7 uniprotkb:Q5XWF0 uniprotkb:Q6QT54 uniprotkb:Q9UDJ3 uniprotkb:Q9UMH0 uniprotkb:Q9UQ96 ensembl:ENSP00000458742.1 |
| Alternative identifier for interactor B | intact:EBI-373586 uniprotkb:Q9BWH3 uniprotkb:Q9UL47 uniprotkb:D3DN89 ensembl:ENSP00000264235.9 |
| Aliases for A | psi-mi:tau_human(display_long) uniprotkb:MAPT(gene name) psi-mi:MAPT(display_short) uniprotkb:MTBT1(gene name synonym) uniprotkb:TAU(gene name synonym) uniprotkb:Neurofibrillary tangle protein(gene name synonym) uniprotkb:Paired helical filament-tau(gene name synonym) uniprotkb:MAPTL(gene name synonym) |
| Aliases for B | psi-mi:gsk3b_human(display_long) uniprotkb:GSK3B(gene name) psi-mi:GSK3B(display_short) uniprotkb:Serine/threonine-protein kinase GSK3B(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Ko et al. (2019) |
| Identifier of the publication | pubmed:31640277 imex:IM-29197 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0914"(association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-26880483 imex:IM-29197-1 |
| Confidence score | intact-miscore:0.66 |
| Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:Fig. 1 comment:"\"To determine whether GSKIP/GSK-3beta/Tau could form an assembly, co-IP assay using GFP–Tau was used to pull down GSK3beta, GSKIP, and PKA RII, as shown in Figure 1. In addition, the complex binding ability of GSKIP was a total loss in the L130P mutant form (Figure 1, right panel, line 3 in lane 3). Moreover, our data showed that PKA RII could not be pulled down by either V41P/L45P or the L130P mutant\"" curation depth:imex curation dataset:Brain Disease - Neurological Diseases & Disorders dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases. dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-293) taxid:9606(Homo sapiens HEK293 embryonic kidney cell) |
| Parameters of the interaction | - |
| Creation date | 2021/03/18 |
| Update date | 2024/08/20 |
| negative Boolean value | false |
| Feature(s) for interactor A | green fluorescent protein tag:?-? |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Anti tag western blot |
| Participant identification method for interactor B | Anti tag western blot |