Curation Details
Interaction ID: IM-29041-11

Unique identifier for interactor Arhea:"RHEA:57720"
Unique identifier for interactor Buniprotkb:Q9HD23
Alternative identifier for interactor Aintact:EBI-25825251
intenz:7.1.2.2
signor:SIGNOR-C264
Alternative identifier for interactor Bintact:EBI-6164303
uniprotkb:B4DQL2
uniprotkb:A8K4U3
uniprotkb:B3KNN2
uniprotkb:Q5T3Y1
uniprotkb:Q6NTG4
uniprotkb:Q96KF8
uniprotkb:Q9BVP1
ensembl:ENSP00000367637.3
Aliases for Apsi-mi:mito_f1f0_atp_synthase_human(display_short)
psi-mi:"RHEA:57720"(display_long)
intact:Mitochondrial respiratory chain complex V(complex synonym)
intact:Mitochondrial proton-transporting ATP synthase complex(complex recommended name)
intact:"3xATP5F1A:3xATP5F1B:ATP5F1C:ATP5F1D:ATP5F1E:ATP5F1EP2:ATP5MC1:ATP5MC2:ATP5MC3:ATP5MD:ATP5ME:ATP5MF:ATP5MG:ATP5MGL:ATP5MPL:ATP5PB:ATP5PD:ATP5PF:ATP5PO:MT-ATP6:MT-ATP8:"(complex systematic name)
intact:F1-F0 ATP synthase complex(synonym)
intact:F1-Fo ATP synthase complex(synonym)
Aliases for Bpsi-mi:mrs2_human(display_long)
uniprotkb:MRS2(gene name)
psi-mi:MRS2(display_short)
uniprotkb:HPT(gene name synonym)
uniprotkb:MRS2-like protein(gene name synonym)
uniprotkb:MRS2L(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorTebbenkamp et al. (2018)
Identifier of the publicationpubmed:30318146
imex:IM-29041
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-27023797
imex:IM-29041-11
Confidence scoreintact-miscore:0.35
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AStable complex
Interactor type BProtein
Annotations for the interactionfigure legend:Fig. 2K
comment:To further confirm the interaction between DNAJC30 and ATP synthase, we isolated mitochondria from human STC and immunoprecipitated the intact ATP synthase.
comment:"\"We captured proteins of both F0 and F1 subunits as well as DNAJC30 (Figure 2K) and were able to confirm another interacting protein from the Y2H screen, the magnesium transporter MRS2.\""
curation depth:imex curation
dataset:Brain Disease - Neurological Diseases & Disorders
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-brain-cortex)
taxid:9606(Homo sapiens brain cortex)
Parameters of the interaction-
Creation date2021/06/26
Update date2025/02/28
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot