| Unique identifier for interactor A | uniprotkb:P05787 |
| Unique identifier for interactor B | uniprotkb:P18031 |
| Alternative identifier for interactor A | intact:EBI-297852 uniprotkb:Q14099 uniprotkb:Q14716 uniprotkb:Q14717 uniprotkb:Q53GJ0 uniprotkb:Q6DHW5 uniprotkb:Q6GMY0 uniprotkb:Q6P4C7 uniprotkb:Q96J60 uniprotkb:A8K4H3 uniprotkb:B0AZN5 uniprotkb:F8VXB4 ensembl:ENSP00000293308.6 ensembl:ENSP00000447402.1 ensembl:ENSP00000447566.1 ensembl:ENSP00000509398.1 |
| Alternative identifier for interactor B | intact:EBI-968788 uniprotkb:Q5TGD8 uniprotkb:Q9BQV9 uniprotkb:Q9NQQ4 ensembl:ENSP00000360683.3 |
| Aliases for A | psi-mi:k2c8_human(display_long) uniprotkb:Keratin-8(gene name synonym) uniprotkb:KRT8(gene name) psi-mi:KRT8(display_short) uniprotkb:CYK8(gene name synonym) uniprotkb:Cytokeratin-8(gene name synonym) uniprotkb:Type-II keratin Kb8(gene name synonym) |
| Aliases for B | psi-mi:ptn1_human(display_long) uniprotkb:PTPN1(gene name) psi-mi:PTPN1(display_short) uniprotkb:PTP1B(gene name synonym) uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0663"(confocal microscopy) |
| First author | Snider et al. (2013) |
| Identifier of the publication | pubmed:24003221 imex:IM-28997 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0403"(colocalization) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-26987972 imex:IM-28997-3 |
| Confidence score | intact-miscore:0.46 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:Fig. 5A-B comment:"\"After transient overexpression into HepG2 cells, we noted a partial K8-PTP1B co-localization with a more diffuse filament staining pattern in the PTP1B-expressing cells (Fig. 5A and inset).\"" curation depth:imex curation dataset:Brain Disease - Neurological Diseases & Disorders full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-hep_g2) taxid:9606(Homo sapiens HepG2 hepatocellular carcinoma cell) |
| Parameters of the interaction | - |
| Creation date | 2021/05/26 |
| Update date | 2024/07/17 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | ha tag:n-n mutation increasing interaction strength:181-181 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Immunostaining |
| Participant identification method for interactor B | Immunostaining |