Unique identifier for interactor A | uniprotkb:O76024 |
Unique identifier for interactor B | uniprotkb:P05026 |
Alternative identifier for interactor A | intact:EBI-720609 uniprotkb:D3DVT1 ensembl:ENSP00000226760.1 ensembl:ENSP00000423337.1 ensembl:ENSP00000506978.1 uniprotkb:Q8N6I3 uniprotkb:Q9UNW6 uniprotkb:B2R797 |
Alternative identifier for interactor B | intact:EBI-714630 ensembl:ENSP00000356789.3 ensembl:ENSP00000356790.1 ensembl:ENSP00000509039.1 ensembl:ENSP00000509517.1 uniprotkb:Q5TGZ3 |
Aliases for A | psi-mi:wfs1_human(display_long) uniprotkb:WFS1(gene name) psi-mi:WFS1(display_short) |
Aliases for B | psi-mi:at1b1_human(display_long) uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym) uniprotkb:ATP1B1(gene name) psi-mi:ATP1B1(display_short) uniprotkb:ATP1B(gene name synonym) |
Interaction detection methods | psi-mi:"MI:0018"(two hybrid) |
First author | Zatyka et al. (2008) |
Identifier of the publication | imex:IM-28979 pubmed:17947299 |
NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
Interaction types | psi-mi:"MI:0915"(physical association) |
Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
Interaction identifier(s) in the corresponding source database | intact:EBI-26982152 imex:IM-28979-1 |
Confidence score | intact-miscore:0.58 |
Complex expansion | - |
Biological role A | Unspecified role |
Biological role B | Unspecified role |
Experimental role A | Bait |
Experimental role B | Prey |
Interactor type A | Protein |
Interactor type B | Protein |
Annotations for the interaction | figure legend:NA comment:we undertook a yeast two-hybrid screen using the WFS1 Cterminal domain as bait in a human cDNA library. Using this and complementary approaches we identify the Na+/K+ATPase beta-1 subunit as a novel interacting partner dataset:Brain Disease - Neurological Diseases & Disorders dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases. dataset:Diabetes - Interactions investigated in the context of Diabetes full coverage:Only protein-protein interactions curation depth:imex curation |
NCBI Taxonomy identifier for the host organism | taxid:4932(yeasx) taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") |
Parameters of the interaction | - |
Creation date | 2021/05/28 |
Update date | 2021/05/28 |
negative Boolean value | false |
Feature(s) for interactor A | sufficient binding region:652-890 |
Feature(s) for interactor B | sufficient binding region:113-303 |
Stoichiometry for interactor A | - |
Stoichiometry for interactor B | - |
Participant identification method for interactor A | Nucleotide sequence identification |
Participant identification method for interactor B | Nucleotide sequence identification |