Curation Details
Interaction ID: IM-28947-5

Unique identifier for interactor Auniprotkb:Q15389
Unique identifier for interactor Buniprotkb:Q02763
Alternative identifier for interactor Aintact:EBI-2922365
uniprotkb:Q5HYA0
ensembl:ENSP00000428340.1
Alternative identifier for interactor Bintact:EBI-2257090
uniprotkb:A8K6W0
uniprotkb:Q5TCU2
uniprotkb:B4DH20
uniprotkb:B4DHD3
uniprotkb:E7EWI2
uniprotkb:Q8IV34
uniprotkb:D3DRK5
ensembl:ENSP00000369375.4
Aliases for Apsi-mi:angp1_human(display_long)
uniprotkb:ANGPT1(gene name)
psi-mi:ANGPT1(display_short)
uniprotkb:KIAA0003(gene name synonym)
Aliases for Bpsi-mi:tie2_human(display_long)
uniprotkb:TEK(gene name)
psi-mi:TEK(display_short)
uniprotkb:TIE2(gene name synonym)
uniprotkb:Tyrosine-protein kinase receptor TIE-2(gene name synonym)
uniprotkb:Tyrosine-protein kinase receptor TEK(gene name synonym)
uniprotkb:Tunica interna endothelial cell kinase(gene name synonym)
uniprotkb:p140 TEK(gene name synonym)
uniprotkb:Endothelial tyrosine kinase(gene name synonym)
uniprotkb:Tyrosine kinase with Ig and EGF homology domains-2(gene name synonym)
uniprotkb:VMCM(gene name synonym)
uniprotkb:VMCM1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorThomson et al. (2017)
Identifier of the publicationpubmed:29106382
imex:IM-28947
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26959780
imex:IM-28947-5
Confidence scoreintact-miscore:0.61
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:Fig. 6C
dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2021/04/22
Update date2021/04/22
negative Boolean valuefalse
Feature(s) for interactor Amutation with no effect:249-249
flag tag:c-c
Feature(s) for interactor Bhis tag:c-c
fc-igg tag:c-c
sufficient binding region:23-745
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot