Unique identifier for interactor A | uniprotkb:Q15389 |
Unique identifier for interactor B | uniprotkb:Q15389 |
Alternative identifier for interactor A | intact:EBI-2922365 uniprotkb:Q5HYA0 ensembl:ENSP00000428340.1 |
Alternative identifier for interactor B | intact:EBI-2922365 uniprotkb:Q5HYA0 ensembl:ENSP00000428340.1 |
Aliases for A | psi-mi:angp1_human(display_long) uniprotkb:ANGPT1(gene name) psi-mi:ANGPT1(display_short) uniprotkb:KIAA0003(gene name synonym) |
Aliases for B | psi-mi:angp1_human(display_long) uniprotkb:ANGPT1(gene name) psi-mi:ANGPT1(display_short) uniprotkb:KIAA0003(gene name synonym) |
Interaction detection methods | psi-mi:"MI:0807"(comigration in gel electrophoresis) |
First author | Thomson et al. (2017) |
Identifier of the publication | pubmed:29106382 imex:IM-28947 |
NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
Interaction types | psi-mi:"MI:0915"(physical association) |
Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
Interaction identifier(s) in the corresponding source database | intact:EBI-26959717 imex:IM-28947-1 |
Confidence score | intact-miscore:0.52 |
Complex expansion | - |
Biological role A | Unspecified role |
Biological role B | Unspecified role |
Experimental role A | Neutral component |
Experimental role B | Neutral component |
Interactor type A | Protein |
Interactor type B | Protein |
Annotations for the interaction | figure legend:Fig. 6A comment:under nonreducing conditions, WT ANGPT1 protein was predominantly grouped in high-order multimers of greater than 250 kDa, consistent with earlier reports curation depth:imex curation dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease full coverage:Only protein-protein interactions |
NCBI Taxonomy identifier for the host organism | taxid:9606(human-293) taxid:9606(Homo sapiens HEK293 embryonic kidney cell) |
Parameters of the interaction | - |
Creation date | 2021/04/22 |
Update date | 2024/11/14 |
negative Boolean value | false |
Feature(s) for interactor A | flag tag:c-c mutation with no effect:249-249 mutation disrupting interaction strength:236-498 mutation disrupting interaction strength:494-498 necessary binding region:494-498 |
Feature(s) for interactor B | flag tag:c-c mutation with no effect:249-249 mutation disrupting interaction strength:236-498 mutation disrupting interaction strength:494-498 necessary binding region:494-498 |
Stoichiometry for interactor A | - |
Stoichiometry for interactor B | - |
Participant identification method for interactor A | Confirmation by molecular weight |
Participant identification method for interactor B | Confirmation by molecular weight |