Curation Details
Interaction ID: IM-28925-1

Unique identifier for interactor Auniprotkb:Q96PU8
Unique identifier for interactor Buniprotkb:Q9UDY8
Alternative identifier for interactor Aintact:EBI-945792
uniprotkb:Q2I375
uniprotkb:Q5MJQ1
uniprotkb:Q969L9
uniprotkb:Q96EJ3
uniprotkb:Q96KA3
uniprotkb:Q96PU6
uniprotkb:Q96PU7
uniprotkb:Q9P0X6
uniprotkb:Q9P0X7
uniprotkb:Q9P0X8
uniprotkb:Q9P0X9
uniprotkb:Q9P0Y0
uniprotkb:Q9P0Y1
ensembl:ENSP00000355094.3
Alternative identifier for interactor Bintact:EBI-1047372
uniprotkb:Q9NTB7
uniprotkb:Q9ULX4
ensembl:ENSP00000497997.1
Aliases for Apsi-mi:qki_human(display_long)
uniprotkb:QKI(gene name)
psi-mi:QKI(display_short)
uniprotkb:HKQ(gene name synonym)
uniprotkb:Protein quaking(gene name synonym)
Aliases for Bpsi-mi:malt1_human(display_long)
uniprotkb:MALT lymphoma-associated translocation(gene name synonym)
uniprotkb:Paracaspase(gene name synonym)
uniprotkb:MALT1(gene name)
psi-mi:MALT1(display_short)
uniprotkb:MLT(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorJacobs et al. (2020)
Identifier of the publicationimex:IM-28925
pubmed:31774199
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26969019
imex:IM-28925-1
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 7b,c
antagonist:"\"pecazine: CHEBI:135324\""
antagonist:Z-VRPR-FMK, MALT1 inhibitor
comment:"\"This showed that MALT1 was pulled down with QKI in GSC#1 and GSC#9, and vice versa (Fig 7B). Because MALT1 appeared excluded from nuclear fractions, the QKI/MALT1 interaction most likely occurs in the cytosol (Fig EV4C). Binding was, however, reduced in cells exposed to MPZ or Z-VRPR-FMK (Fig 7C).\""
curation depth:imex curation
dataset:Brain Disease - Neurological Diseases & Disorders
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-GSCs)
taxid:9606(Homo sapiens glioblastoma multiforme cancer stem cell)
Parameters of the interaction-
Creation date2021/04/29
Update date2024/09/03
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot