| Unique identifier for interactor A | uniprotkb:P61981 |
| Unique identifier for interactor B | uniprotkb:P12814 |
| Alternative identifier for interactor A | intact:EBI-359832 uniprotkb:O70457 uniprotkb:P35214 uniprotkb:Q6FH52 uniprotkb:Q9UDP2 ensembl:ENSP00000306330.3 uniprotkb:Q9UN99 |
| Alternative identifier for interactor B | intact:EBI-351710 intact:EBI-3866221 uniprotkb:B3V8S3 uniprotkb:B4DHH3 ensembl:ENSP00000193403.6 uniprotkb:Q9BTN1 uniprotkb:Q1HE25 uniprotkb:B7TY16 |
| Aliases for A | psi-mi:1433g_human(display_long) uniprotkb:YWHAG(gene name) psi-mi:YWHAG(display_short) uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) |
| Aliases for B | psi-mi:actn1_human(display_long) uniprotkb:ACTN1(gene name) psi-mi:ACTN1(display_short) uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym) uniprotkb:Non-muscle alpha-actinin-1(gene name synonym) uniprotkb:F-actin cross-linking protein(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Zhao et al. (2017) |
| Identifier of the publication | pubmed:29100370 imex:IM-28920 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0914"(association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-26966879 imex:IM-28920-23 |
| Confidence score | intact-miscore:0.35 |
| Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | comment:"\"We considered the PAK4 interactome as the proteins passing a combined cut-off of based on statistical testing (t-test with multiple hypothesis correction; p ≤ 0.05; 5% FDR); and FLAG-PAK4 signals above the 99.9 % confidence interval of the FLAG-BAP signal distribution. In total, 313 proteins passed our PAK4 interactome cut-off; 233 in the whole cell, 167 in the cytoplasmic fraction and 54 in the nuclear fraction (Figure 1C and Supplementary Table 1).\"" figure legend:ST1 dataset:Cancer - Interactions investigated in the context of cancer full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-mcf7) taxid:9606(Homo sapiens MCF-7 mammary adenocarcinoma cell) |
| Parameters of the interaction | - |
| Creation date | 2018/11/26 |
| Update date | 2021/07/20 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | De novo protein sequencing by mass spectrometry |
| Participant identification method for interactor B | De novo protein sequencing by mass spectrometry |