Curation Details
Interaction ID: IM-28920-11

Unique identifier for interactor Auniprotkb:O00401
Unique identifier for interactor Buniprotkb:O96013
Alternative identifier for interactor Aintact:EBI-957615
uniprotkb:A1JUI9
ensembl:ENSP00000223023.4
uniprotkb:Q7Z746
Alternative identifier for interactor Bintact:EBI-713738
ensembl:ENSP00000351049.2
ensembl:ENSP00000353625.3
ensembl:ENSP00000469413.1
uniprotkb:Q8N4E1
uniprotkb:Q8NCH5
uniprotkb:Q8NDE3
uniprotkb:Q9BU33
uniprotkb:Q9ULS8
uniprotkb:B4DGG6
Aliases for Apsi-mi:wasl_human(display_long)
uniprotkb:WASL(gene name)
psi-mi:WASL(display_short)
uniprotkb:Neural Wiskott-Aldrich syndrome protein(gene name synonym)
Aliases for Bpsi-mi:pak4_human(display_long)
uniprotkb:p21-activated kinase 4(gene name synonym)
uniprotkb:PAK4(gene name)
psi-mi:PAK4(display_short)
uniprotkb:KIAA1142(gene name synonym)
Interaction detection methodspsi-mi:"MI:0415"(enzymatic study)
First authorZhao et al. (2017)
Identifier of the publicationpubmed:29100370
imex:IM-28920
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26967922
imex:IM-28920-11
Confidence scoreintact-miscore:0.62
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:SF3
comment:"\"We here used recombinant PAK4 kinase domain because it displayed a more efficient phosphorylation of the VCA domain than full-length PAK4 (Supplementary Figure 3A).\""
dataset:Cancer - Interactions investigated in the context of cancer
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2018/11/26
Update date2021/04/30
negative Boolean valuefalse
Feature(s) for interactor Aglutathione s tranferase tag:?-?
sufficient binding region:392-505
Feature(s) for interactor Bsufficient binding region:286-591
glutathione s tranferase tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AMolecular weight estimation by autoradiography
Participant identification method for interactor BMolecular weight estimation by autoradiography