| Unique identifier for interactor A | uniprotkb:O96013 |
| Unique identifier for interactor B | uniprotkb:Q8NC51 |
| Alternative identifier for interactor A | intact:EBI-713738 uniprotkb:Q8N4E1 uniprotkb:Q8NCH5 uniprotkb:Q8NDE3 uniprotkb:Q9BU33 uniprotkb:Q9ULS8 uniprotkb:B4DGG6 ensembl:ENSP00000351049.2 ensembl:ENSP00000353625.3 ensembl:ENSP00000469413.1 |
| Alternative identifier for interactor B | intact:EBI-523558 uniprotkb:Q8WUH0 uniprotkb:Q96SE2 uniprotkb:Q9BTY3 uniprotkb:Q9BUM4 uniprotkb:Q9Y367 uniprotkb:Q9Y4S3 uniprotkb:Q5VU19 intact:EBI-1058614 uniprotkb:Q5VU20 uniprotkb:Q5VU22 ensembl:ENSP00000360034.2 |
| Aliases for A | psi-mi:pak4_human(display_long) uniprotkb:p21-activated kinase 4(gene name synonym) uniprotkb:PAK4(gene name) psi-mi:PAK4(display_short) uniprotkb:KIAA1142(gene name synonym) |
| Aliases for B | psi-mi:serb1_human(display_long) uniprotkb:PAI1 RNA-binding protein 1(gene name synonym) uniprotkb:SERBP1(gene name) psi-mi:SERBP1(display_short) uniprotkb:PAIRBP1(gene name synonym) uniprotkb:Plasminogen activator inhibitor 1 RNA-binding protein(gene name synonym) uniprotkb:CGI-55(orf name) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Zhao et al. (2017) |
| Identifier of the publication | pubmed:29100370 imex:IM-28920 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0914"(association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-26966699 imex:IM-28920-1 |
| Confidence score | intact-miscore:0.35 |
| Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:ST1 comment:"\"We considered the PAK4 interactome as the proteins passing a combined cut-off of based on statistical testing (t-test with multiple hypothesis correction; p ≤ 0.05; 5% FDR); and FLAG-PAK4 signals above the 99.9 % confidence interval of the FLAG-BAP signal distribution. In total, 313 proteins passed our PAK4 interactome cut-off; 233 in the whole cell, 167 in the cytoplasmic fraction and 54 in the nuclear fraction (Figure 1C and Supplementary Table 1).\"" curation depth:imex curation dataset:Cancer - Interactions investigated in the context of cancer full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-mcf7) taxid:9606(Homo sapiens MCF-7 mammary adenocarcinoma cell) |
| Parameters of the interaction | - |
| Creation date | 2018/11/26 |
| Update date | 2024/09/05 |
| negative Boolean value | false |
| Feature(s) for interactor A | flag tag:?-? |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | De novo protein sequencing by mass spectrometry |
| Participant identification method for interactor B | De novo protein sequencing by mass spectrometry |