| Unique identifier for interactor A | uniprotkb:Q8IXI2 |
| Unique identifier for interactor B | uniprotkb:Q9NRI5 |
| Alternative identifier for interactor A | intact:EBI-1396430 ensembl:ENSP00000334724.6 uniprotkb:A4FVB6 uniprotkb:Q6NUR3 uniprotkb:Q6P9F8 uniprotkb:Q6PJG1 uniprotkb:Q6YMW8 uniprotkb:Q86UB0 uniprotkb:Q8IW28 uniprotkb:Q8IXJ7 uniprotkb:Q9H067 uniprotkb:Q9H9N8 uniprotkb:Q9NUZ2 uniprotkb:A6NFV0 uniprotkb:B4DG48 uniprotkb:J9JIH9 |
| Alternative identifier for interactor B | intact:EBI-529989 uniprotkb:O75045 uniprotkb:Q5VT44 uniprotkb:Q5VT45 uniprotkb:Q8IXJ0 uniprotkb:Q8IXJ1 uniprotkb:Q9BX19 uniprotkb:Q9NRI3 uniprotkb:Q9NRI4 uniprotkb:C9J6D0 intact:EBI-28977396 uniprotkb:A6NLH2 uniprotkb:C4P095 uniprotkb:C4P0A1 uniprotkb:C4P0A3 uniprotkb:C4P0B3 uniprotkb:C4P091 uniprotkb:C4P0B6 uniprotkb:C4P0C1 ensembl:ENSP00000403888.4 |
| Aliases for A | psi-mi:miro1_human(display_long) uniprotkb:Ras homolog gene family member T1(gene name synonym) uniprotkb:Rac-GTP-binding protein-like protein(gene name synonym) uniprotkb:RHOT1(gene name) psi-mi:RHOT1(display_short) uniprotkb:ARHT1(gene name synonym) |
| Aliases for B | psi-mi:disc1_human(display_long) uniprotkb:DISC1(gene name) psi-mi:DISC1(display_short) uniprotkb:KIAA0457(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Norkett et al. (2019) |
| Identifier of the publication | imex:IM-28852 pubmed:32637409 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-26902647 imex:IM-28852-1 |
| Confidence score | intact-miscore:0.40 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:fig.2 e-f comment:"\"We carried out GFP trap coimmunoprecipitation experiments from COS7 cells expressing untagged, WTDISC1, and GFP-tagged WT, V13, or N18 Miro1 to mimic GTP- and GDP-bound states, respectively. Interestingly, Western blot analysis revealed that more DISC1 is immunoprecipitated with V13 Miro1 compared to WT Miro1 (Figure 2E, quantified in 2F, normalized DISC1 intensity for WT Miro1 = 1.0, for V13 Miro1 = 5.2 ± 2.1, p = 0.05), indicating that DISC1 preferentially interacts with the GTP-bound Miro mimic.\"" dataset:Brain Disease - Neurological Diseases & Disorders curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9534(chlae-cos_7) taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) |
| Parameters of the interaction | - |
| Creation date | 2021/03/15 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | green fluorescent protein tag:?-? mutation with no effect:18-18 mutation increasing interaction:13-13 |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |