Curation Details
Interaction ID: IM-28819-8

Unique identifier for interactor Auniprotkb:Q13501
Unique identifier for interactor Buniprotkb:P34972
Alternative identifier for interactor Aintact:EBI-307104
uniprotkb:Q13446
uniprotkb:Q9BUV7
uniprotkb:Q9BVS6
uniprotkb:Q9UEU1
uniprotkb:A6NFN7
uniprotkb:B2R661
uniprotkb:B3KUW5
intact:EBI-28976133
ensembl:ENSP00000374455.4
ensembl:ENSP00000491834.2
ensembl:ENSP00000495843.2
Alternative identifier for interactor Bintact:EBI-2835940
uniprotkb:C6ES44
uniprotkb:Q6NSY0
uniprotkb:Q5JRH7
uniprotkb:Q6B0G7
uniprotkb:Q4VBK8
ensembl:ENSP00000363596.4
Aliases for Apsi-mi:sqstm_human(display_long)
uniprotkb:SQSTM1(gene name)
psi-mi:SQSTM1(display_short)
uniprotkb:ORCA(gene name synonym)
uniprotkb:OSIL(gene name synonym)
uniprotkb:Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa(gene name synonym)
uniprotkb:Ubiquitin-binding protein p62(gene name synonym)
uniprotkb:EBI3-associated protein of 60 kDa(gene name synonym)
Aliases for Bpsi-mi:cnr2_human(display_long)
uniprotkb:CNR2(gene name)
psi-mi:CNR2(display_short)
uniprotkb:CX5(gene name synonym)
uniprotkb:CB2A(gene name synonym)
uniprotkb:CB2B(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorSharaf et al. (2018)
Identifier of the publicationimex:IM-28819
pubmed:31616248
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26900288
imex:IM-28819-8
Confidence scoreintact-miscore:0.56
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f6b
comment:"\"We designed expression constructs deleting the three intracellular loops and the C-terminus of the CB2 receptor (Figure 5A). Surprisingly none of these deletion constructs altered the interaction of CB2 with p62 in co-IP studies if correlated to the different expression levels in the input and the IPs (Figure 5B).\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2021/03/18
Update date2024/11/15
negative Boolean valuefalse
Feature(s) for interactor Anecessary binding region:122-168
flag tag:?-?
Feature(s) for interactor Bha tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot