Curation Details
Interaction ID: IM-28815-11

Unique identifier for interactor Auniprotkb:Q99MQ3
Unique identifier for interactor Buniprotkb:O60260
Alternative identifier for interactor Aintact:EBI-2257664
uniprotkb:A2AM77
uniprotkb:Q7TMZ3
uniprotkb:Q811I8
uniprotkb:Q91XU5
ensembl:ENSMUSP00000030536.7
Alternative identifier for interactor Bintact:EBI-716346
uniprotkb:A8K975
ensembl:ENSP00000355865.1
uniprotkb:A3FG77
uniprotkb:Q5TFV8
uniprotkb:Q6Q2I6
uniprotkb:Q8NI41
uniprotkb:Q8NI43
uniprotkb:Q8NI44
uniprotkb:D3JZW7
uniprotkb:D3K2X0
uniprotkb:Q5VVX4
uniprotkb:Q8WW07
Aliases for Apsi-mi:pink1_mouse(display_long)
uniprotkb:Pink1(gene name)
psi-mi:Pink1(display_short)
uniprotkb:PTEN-induced putative kinase protein 1(gene name synonym)
uniprotkb:BRPK(gene name synonym)
Aliases for Bpsi-mi:prkn_human(display_long)
uniprotkb:PRKN(gene name)
psi-mi:PRKN(display_short)
uniprotkb:PARK2(gene name synonym)
uniprotkb:Parkin RBR E3 ubiquitin-protein ligase(gene name synonym)
uniprotkb:Parkinson juvenile disease protein 2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorChen et al. (2018)
Identifier of the publicationimex:IM-28815
pubmed:29899409
NCBI Taxonomy identifier for interactor Ataxid:10090(mouse)
taxid:10090(Mus musculus)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26877589
imex:IM-28815-11
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F7C
comment:"\"Furthermore, we measured the interaction between PINK1 and Parkin as well as Parkin phosphorylation at serine 65 in SN4741 cells. As expected, we observed that SB203580 restored the reduction of PINK1–Parkin interaction and co-localization (Fig. 4c–f)\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:10090(mouse_sn4741)
taxid:10090(mouse_sn4741)
Parameters of the interaction-
Creation date2021/02/19
Update date2021/03/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bmutation decreasing interaction:131-131
green fluorescent protein tag:n-n
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot