Curation Details
Interaction ID: IM-28778-5

Unique identifier for interactor Achebi:"CHEBI:76792"
Unique identifier for interactor Buniprotkb:P51608
Alternative identifier for interactor Aintact:EBI-26617992
Alternative identifier for interactor Bintact:EBI-1189067
ensembl:ENSP00000301948.6
uniprotkb:O15233
uniprotkb:Q6QHH9
uniprotkb:Q7Z384
Aliases for Apsi-mi:"5-(hydroxymethyl)cytosine"(display_short)
psi-mi:"CHEBI:76792"(display_long)
intact:"4-Amino-5-(hydroxymethyl)-2(1H)-pyrimidinone"(synonym)
intact:5-hydroxymethylcytosine(synonym)
intact:"4-amino-5-(hydroxymethyl)pyrimidin-2(1H)-one"(iupac name)
Aliases for Bpsi-mi:mecp2_human(display_long)
uniprotkb:MECP2(gene name)
psi-mi:MECP2(display_short)
Interaction detection methodspsi-mi:"MI:0107"(surface plasmon resonance)
First authorMellén et al. (2012)
Identifier of the publicationpubmed:23260135
imex:IM-28778
NCBI Taxonomy identifier for interactor Ataxid:-2(chemical synthesis)
taxid:-2("Chemical synthesis (Chemical synthesis)")
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26618817
imex:IM-28778-5
Confidence scoreintact-miscore:0.56
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type ASmall molecule
Interactor type BProtein
Annotations for the interactionfigure legend:Fig. 5B-C
dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease
dataset:Brain Disease - Neurological Diseases & Disorders
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2021/02/09
Update date2021/02/10
negative Boolean valuefalse
Feature(s) for interactor Abiotin tag:?-?
Feature(s) for interactor Bsufficient binding region:1-205
mutation disrupting interaction strength:133-133
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant