Curation Details
Interaction ID: IM-28753-14

Unique identifier for interactor Auniprotkb:P61978
Unique identifier for interactor Buniprotkb:Q17R98
Alternative identifier for interactor Aintact:EBI-304185
intact:EBI-28971491
uniprotkb:Q07244
uniprotkb:Q15671
uniprotkb:Q59F98
uniprotkb:Q60577
uniprotkb:Q922Y7
uniprotkb:Q96J62
uniprotkb:Q5T6W4
intact:EBI-3440248
uniprotkb:Q6IBN1
ensembl:ENSP00000317788.4
ensembl:ENSP00000353552.5
ensembl:ENSP00000515619.1
ensembl:ENSP00000515654.1
ensembl:ENSP00000515655.1
ensembl:ENSP00000515656.1
ensembl:ENSP00000515661.1
Alternative identifier for interactor Bintact:EBI-5564776
uniprotkb:B7ZL52
uniprotkb:Q7Z4S7
uniprotkb:Q8N279
ensembl:ENSP00000421863.1
Aliases for Apsi-mi:hnrpk_human(display_long)
uniprotkb:HNRNPK(gene name)
psi-mi:HNRNPK(display_short)
uniprotkb:HNRPK(gene name synonym)
uniprotkb:Transformation up-regulated nuclear protein(gene name synonym)
Aliases for Bpsi-mi:zn827_human(display_long)
uniprotkb:ZNF827(gene name)
psi-mi:ZNF827(display_short)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorHollensen et al. (2020)
Identifier of the publicationimex:IM-28753
pubmed:33174841
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26903727
imex:IM-28753-14
Confidence scoreintact-miscore:0.35
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 6e
comment:"\"To address whether ZNF827 and hnRNP K interact, we next performed ZNF827 immunoprecipitation and found it to strongly associate with hnRNP K and to a lesser extent with hnRNP L in nucleoplasmic extracts (Figure 6E, left). Upon sonication of the remainder from the Triton X-100 extracted cleared lysates (chromatin enriched), we observed an even stronger association of hnRNP K with ZNF827, further suggesting that the complex is chromatin bound (Figure 6E, right).\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-lan_5)
taxid:9606(Homo sapiens LAN-5 neuroblastoma cell)
Parameters of the interaction-
Creation date2021/02/10
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot