Curation Details
Interaction ID: IM-28737-7

Unique identifier for interactor Auniprotkb:Q99650
Unique identifier for interactor Buniprotkb:O75306
Alternative identifier for interactor Aintact:EBI-2804080
uniprotkb:Q96QJ6
uniprotkb:Q6P4E8
ensembl:ENSP00000274276.3
Alternative identifier for interactor Bintact:EBI-1224806
uniprotkb:Q5VTW0
uniprotkb:Q969P3
uniprotkb:Q9UEV3
uniprotkb:J3KPM7
uniprotkb:D3DVG7
intact:EBI-11120296
ensembl:ENSP00000356972.3
ensembl:ENSP00000503117.1
ensembl:ENSP00000503989.1
ensembl:ENSP00000504199.1
ensembl:ENSP00000504846.1
intact:EBI-28971126
Aliases for Apsi-mi:osmr_human(display_long)
uniprotkb:OSMRB(gene name synonym)
uniprotkb:Interleukin-31 receptor subunit beta(gene name synonym)
uniprotkb:OSMR(gene name)
psi-mi:OSMR(display_short)
Aliases for Bpsi-mi:ndus2_human(display_long)
uniprotkb:NDUFS2(gene name)
psi-mi:NDUFS2(display_short)
uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)
uniprotkb:Complex I-49kD(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorSharanek et al. (2020)
Identifier of the publicationpubmed:32807793
imex:IM-28737
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26656120
imex:IM-28737-7
Confidence scoreintact-miscore:0.50
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:fig. 2 l-o
comment:"\"Via co-IP of either WCL or purified mitochondrial fractions, we found that OSMR interacted endogenously with both NDUFS1 and NDUFS2 in multiple patient-derived BTSCs (Fig. 2l–o).\""
dataset:Brain Disease - Neurological Diseases & Disorders
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:Cancer - Interactions investigated in the context of cancer
NCBI Taxonomy identifier for the host organismtaxid:9606(human-btsc73)
taxid:9606(Homo sapiens BTSC73 brain tumor stem cell)
Parameters of the interaction-
Creation date2021/02/15
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot