| Unique identifier for interactor A | uniprotkb:Q99650 |
| Unique identifier for interactor B | uniprotkb:P38646 |
| Alternative identifier for interactor A | intact:EBI-2804080 uniprotkb:Q96QJ6 uniprotkb:Q6P4E8 ensembl:ENSP00000274276.3 |
| Alternative identifier for interactor B | intact:EBI-354932 uniprotkb:P30036 uniprotkb:P31932 uniprotkb:Q6GU03 uniprotkb:Q9BWB7 uniprotkb:B2RCM1 uniprotkb:Q1HB43 uniprotkb:Q53H23 uniprotkb:Q9UC56 ensembl:ENSP00000297185.3 |
| Aliases for A | psi-mi:osmr_human(display_long) uniprotkb:OSMRB(gene name synonym) uniprotkb:Interleukin-31 receptor subunit beta(gene name synonym) uniprotkb:OSMR(gene name) psi-mi:OSMR(display_short) |
| Aliases for B | psi-mi:grp75_human(display_long) uniprotkb:HSPA9(gene name) psi-mi:HSPA9(display_short) uniprotkb:GRP75(gene name synonym) uniprotkb:HSPA9B(gene name synonym) uniprotkb:75 kDa glucose-regulated protein(gene name synonym) uniprotkb:Heat shock 70 kDa protein 9(gene name synonym) uniprotkb:Peptide-binding protein 74(gene name synonym) uniprotkb:Mortalin(gene name synonym) uniprotkb:mt-HSP70(gene name synonym) uniprotkb:Heat shock protein family A member 9(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
| First author | Sharanek et al. (2020) |
| Identifier of the publication | pubmed:32807793 imex:IM-28737 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0914"(association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-26656096 imex:IM-28737-3 |
| Confidence score | intact-miscore:0.50 |
| Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:fig. 2c-d comment:"\"We performed co-immunoprecipitation (co-IP) followed by Western blot (WB) analysis, on either whole cell lysates (WCL) or purified mitochondrial fractions, and found that OSMR physically interacted with both mtHSP70 and TIM44 endogenously in multiple patient-derived BTSCs (Fig. 2c–f).\"" dataset:Brain Disease - Neurological Diseases & Disorders curation depth:imex curation full coverage:Only protein-protein interactions dataset:Cancer - Interactions investigated in the context of cancer |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-btsc73) taxid:9606(Homo sapiens BTSC73 brain tumor stem cell) |
| Parameters of the interaction | - |
| Creation date | 2021/02/15 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |