Curation Details
Interaction ID: IM-28651-11

Unique identifier for interactor Auniprotkb:Q9BW27
Unique identifier for interactor Buniprotkb:Q12769
Alternative identifier for interactor Aintact:EBI-716392
intact:EBI-2563151
uniprotkb:Q9H9U1
uniprotkb:Q8NDI4
uniprotkb:B4DMQ3
uniprotkb:B4DPW1
ensembl:ENSP00000245544.4
Alternative identifier for interactor Bintact:EBI-295715
uniprotkb:Q96GB3
uniprotkb:Q9H660
uniprotkb:B4DYE8
uniprotkb:B4E2J9
uniprotkb:Q08AD3
uniprotkb:Q7Z5X6
intact:EBI-2563140
ensembl:ENSP00000511549.1
Aliases for Apsi-mi:nup85_human(display_long)
uniprotkb:PCNT1(gene name synonym)
uniprotkb:Nucleoporin Nup85(gene name synonym)
uniprotkb:85 kDa nucleoporin(gene name synonym)
uniprotkb:Nucleoporin Nup75(gene name synonym)
uniprotkb:Pericentrin-1(gene name synonym)
uniprotkb:FROUNT(gene name synonym)
uniprotkb:NUP85(gene name)
psi-mi:NUP85(display_short)
uniprotkb:NUP75(gene name synonym)
Aliases for Bpsi-mi:nu160_human(display_long)
uniprotkb:NUP160(gene name)
psi-mi:NUP160(display_short)
uniprotkb:KIAA0197(gene name synonym)
uniprotkb:NUP120(gene name synonym)
uniprotkb:Nucleoporin Nup160(gene name synonym)
uniprotkb:160 kDa nucleoporin(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorBraun et al. (2018)
Identifier of the publicationpubmed:30179222
imex:IM-28651
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26589310
imex:IM-28651-11
Confidence scoreintact-miscore:0.59
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:Fig. 2D
comment:"\"A splice site mutant [NM_024844.5:c.405+1G>A] of NUP85 also disrupted this interaction, but a protein sequence for this mutant could not be found. (ClinVar:VCV000590317)\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293t)
taxid:9606(Homo sapiens HEK293T embryonic kidney cell)
Parameters of the interaction-
Creation date2021/01/14
Update date2024/11/28
negative Boolean valuefalse
Feature(s) for interactor Amyc tag:n-n
mutation decreasing interaction strength:645-645
mutation disrupting interaction strength:581-581
mutation with no effect:477-477
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BWestern blot