Curation Details
Interaction ID: IM-28593-1

Unique identifier for interactor Auniprotkb:P31016
Unique identifier for interactor Buniprotkb:P19490
Alternative identifier for interactor Aintact:EBI-375655
uniprotkb:P97631
Alternative identifier for interactor Bintact:EBI-371642
ensembl:ENSRNOP00000064722.3
ensembl:ENSRNOP00055042480
ensembl:ENSRNOP00060032516
ensembl:ENSRNOP00065007367
Aliases for Apsi-mi:dlg4_rat(display_long)
uniprotkb:Dlg4(gene name)
psi-mi:Dlg4(display_short)
uniprotkb:Dlgh4(gene name synonym)
uniprotkb:Postsynaptic density protein 95(gene name synonym)
uniprotkb:Synapse-associated protein 90(gene name synonym)
uniprotkb:Psd95(gene name synonym)
Aliases for Bpsi-mi:gria1_rat(display_long)
uniprotkb:Gria1(gene name)
psi-mi:Gria1(display_short)
uniprotkb:GluR-A(gene name synonym)
uniprotkb:GluR-K1(gene name synonym)
uniprotkb:Glutamate receptor ionotropic, AMPA 1(gene name synonym)
uniprotkb:AMPA-selective glutamate receptor 1(gene name synonym)
uniprotkb:Glur1(gene name synonym)
uniprotkb:GluA1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorSpinelli et al. (2017)
Identifier of the publicationpubmed:29222408
imex:IM-28593
NCBI Taxonomy identifier for interactor Ataxid:10116(rat)
taxid:10116("Rattus norvegicus (Rat)")
NCBI Taxonomy identifier for interactor Btaxid:10116(rat)
taxid:10116("Rattus norvegicus (Rat)")
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26572873
imex:IM-28593-1
Confidence scoreintact-miscore:0.65
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f4d
comment:"\"Insulin and palmitic acid (IPA) treatment did not affect the total amount of both GluA1 and PDS95, but rather decreased the stoichiometry of the binding, suggesting either lower affinity between the two proteins or reduced co-localization in the synaptic membrane.\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:10116(rat-hippocampus_neuron)
taxid:10116(Rattus norvegicus)
Parameters of the interaction-
Creation date2020/12/28
Update date2020/12/28
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot