| Unique identifier for interactor A | uniprotkb:P0DP23 |
| Unique identifier for interactor B | uniprotkb:Q5JU85 |
| Alternative identifier for interactor A | intact:EBI-25817233 ensembl:ENSP00000349467.4 intact:EBI-28973196 uniprotkb:P02593 uniprotkb:P62158 uniprotkb:P70667 uniprotkb:P99014 uniprotkb:Q13942 uniprotkb:Q53S29 uniprotkb:Q61379 uniprotkb:Q61380 uniprotkb:Q96HK3 |
| Alternative identifier for interactor B | intact:EBI-11028607 uniprotkb:B3KT97 uniprotkb:C7SDG1 uniprotkb:Q5JUX1 uniprotkb:O60275 uniprotkb:A0A1W2PQN3 ensembl:ENSP00000495726.1 ensembl:ENSP00000502054.1 |
| Aliases for A | psi-mi:calm1_human(display_long) uniprotkb:CALM1(gene name) psi-mi:CALM1(display_short) uniprotkb:CALM(gene name synonym) uniprotkb:CAM(gene name synonym) uniprotkb:CAM1(gene name synonym) |
| Aliases for B | psi-mi:iqec2_human(display_long) uniprotkb:IQSEC2(gene name) psi-mi:IQSEC2(display_short) uniprotkb:KIAA0522(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0729"(luminescence based mammalian interactome mapping) |
| First author | Rogers et al. (2018) |
| Identifier of the publication | imex:IM-28573 pubmed:30842726 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-26564800 imex:IM-28573-3 |
| Confidence score | intact-miscore:0.56 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:Fig. 2 comment:The binding of calmodulin to wild type and A350V IQSEC2 is increased by calcium. agonist:"\"calcium2+ (CHEBI:29108)\"" curation depth:imex curation dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease full coverage:Only protein-protein interactions dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\"" dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-293t) taxid:9606(Homo sapiens HEK293T embryonic kidney cell) |
| Parameters of the interaction | - |
| Creation date | 2020/12/15 |
| Update date | 2025/08/08 |
| negative Boolean value | false |
| Feature(s) for interactor A | flag tag:c-c |
| Feature(s) for interactor B | renilla luciferase protein tag:n-n mutation disrupting interaction strength:350-350 ha tag:n-n mutation disrupting interaction strength:359-359 mutation disrupting interaction strength:354-355,359-359 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Tag visualisation by luciferase assay |
| Participant identification method for interactor B | Tag visualisation by luciferase assay |