Curation Details
Interaction ID: IM-28561-973

Unique identifier for interactor Auniprotkb:P21964
Unique identifier for interactor Buniprotkb:P51116
Alternative identifier for interactor Aintact:EBI-372265
uniprotkb:Q6IB07
uniprotkb:Q6ICE6
uniprotkb:A8MPV9
intact:EBI-743305
uniprotkb:Q9BWC7
intact:EBI-11576026
ensembl:ENSP00000354511.6
ensembl:ENSP00000384654.2
ensembl:ENSP00000385150.3
ensembl:ENSP00000385917.1
ensembl:ENSP00000503583.1
ensembl:ENSP00000503719.1
ensembl:ENSP00000504402.1
Alternative identifier for interactor Bintact:EBI-740459
uniprotkb:Q8WUM2
uniprotkb:Q86V09
uniprotkb:B2R9M2
uniprotkb:D3DTQ1
ensembl:ENSP00000250113.7
Aliases for Apsi-mi:comt_human(display_long)
uniprotkb:COMT(gene name)
psi-mi:COMT(display_short)
Aliases for Bpsi-mi:fxr2_human(display_long)
uniprotkb:FXR2(gene name)
psi-mi:FXR2(display_short)
uniprotkb:FMR1L2(gene name synonym)
uniprotkb:FMR1 autosomal homolog 2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0398"(two hybrid pooling approach)
First authorSakai et al. (2011)
Identifier of the publicationdoi:10.1126/scitranslmed.3002166
pubmed:21653829
imex:IM-28561
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26511673
imex:IM-28561-973
Confidence scoreintact-miscore:0.37
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST2
comment:"\"Library for Y2H screening used: human brain\""
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn
dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\""
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2020/10/05
Update date2020/12/11
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bsufficient binding region:235-370
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification