Curation Details
Interaction ID: IM-28561-97

Unique identifier for interactor Auniprotkb:P55036
Unique identifier for interactor Buniprotkb:Q05086
Alternative identifier for interactor Aintact:EBI-359318
uniprotkb:Q5VWC5
uniprotkb:Q9NS92
uniprotkb:D3DV16
ensembl:ENSP00000357879.4
Alternative identifier for interactor Bintact:EBI-954357
uniprotkb:P78355
uniprotkb:Q93066
uniprotkb:Q9UEP4
uniprotkb:Q9UEP5
uniprotkb:Q9UEP6
uniprotkb:Q9UEP7
uniprotkb:Q9UEP8
uniprotkb:Q9UEP9
uniprotkb:A8K8Z9
ensembl:ENSP00000497594.1
Aliases for Apsi-mi:psmd4_human(display_long)
uniprotkb:PSMD4(gene name)
psi-mi:PSMD4(display_short)
uniprotkb:MCB1(gene name synonym)
uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)
uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)
uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)
uniprotkb:Antisecretory factor 1(gene name synonym)
Aliases for Bpsi-mi:ube3a_human(display_long)
uniprotkb:E6AP ubiquitin-protein ligase(gene name synonym)
uniprotkb:Oncogenic protein-associated protein E6-AP(gene name synonym)
uniprotkb:Human papillomavirus E6-associated protein(gene name synonym)
uniprotkb:Renal carcinoma antigen NY-REN-54(gene name synonym)
uniprotkb:UBE3A(gene name)
psi-mi:UBE3A(display_short)
uniprotkb:E6AP(gene name synonym)
uniprotkb:EPVE6AP(gene name synonym)
uniprotkb:HPVE6A(gene name synonym)
uniprotkb:HECT-type ubiquitin transferase E3A(gene name synonym)
Interaction detection methodspsi-mi:"MI:0398"(two hybrid pooling approach)
First authorSakai et al. (2011)
Identifier of the publicationdoi:10.1126/scitranslmed.3002166
pubmed:21653829
imex:IM-28561
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26516214
imex:IM-28561-97
Confidence scoreintact-miscore:0.73
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST2
comment:"\"Library for Y2H screening used: human brain\""
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn
dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\""
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2020/10/05
Update date2024/11/28
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bsufficient binding region:1-159
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification