Unique identifier for interactor A | uniprotkb:P55036 |
Unique identifier for interactor B | uniprotkb:Q05086 |
Alternative identifier for interactor A | intact:EBI-359318 uniprotkb:Q5VWC5 uniprotkb:Q9NS92 uniprotkb:D3DV16 ensembl:ENSP00000357879.4 |
Alternative identifier for interactor B | intact:EBI-954357 uniprotkb:P78355 uniprotkb:Q93066 uniprotkb:Q9UEP4 uniprotkb:Q9UEP5 uniprotkb:Q9UEP6 uniprotkb:Q9UEP7 uniprotkb:Q9UEP8 uniprotkb:Q9UEP9 uniprotkb:A8K8Z9 ensembl:ENSP00000497594.1 |
Aliases for A | psi-mi:psmd4_human(display_long) uniprotkb:PSMD4(gene name) psi-mi:PSMD4(display_short) uniprotkb:MCB1(gene name synonym) uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym) uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym) uniprotkb:Multiubiquitin chain-binding protein(gene name synonym) uniprotkb:Antisecretory factor 1(gene name synonym) |
Aliases for B | psi-mi:ube3a_human(display_long) uniprotkb:E6AP ubiquitin-protein ligase(gene name synonym) uniprotkb:Oncogenic protein-associated protein E6-AP(gene name synonym) uniprotkb:Human papillomavirus E6-associated protein(gene name synonym) uniprotkb:Renal carcinoma antigen NY-REN-54(gene name synonym) uniprotkb:UBE3A(gene name) psi-mi:UBE3A(display_short) uniprotkb:E6AP(gene name synonym) uniprotkb:EPVE6AP(gene name synonym) uniprotkb:HPVE6A(gene name synonym) uniprotkb:HECT-type ubiquitin transferase E3A(gene name synonym) |
Interaction detection methods | psi-mi:"MI:0398"(two hybrid pooling approach) |
First author | Sakai et al. (2011) |
Identifier of the publication | doi:10.1126/scitranslmed.3002166 pubmed:21653829 imex:IM-28561 |
NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
Interaction types | psi-mi:"MI:0915"(physical association) |
Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
Interaction identifier(s) in the corresponding source database | intact:EBI-26516214 imex:IM-28561-97 |
Confidence score | intact-miscore:0.73 |
Complex expansion | - |
Biological role A | Unspecified role |
Biological role B | Unspecified role |
Experimental role A | Prey |
Experimental role B | Bait |
Interactor type A | Protein |
Interactor type B | Protein |
Annotations for the interaction | figure legend:ST2 comment:"\"Library for Y2H screening used: human brain\"" curation depth:imex curation full coverage:Only protein-protein interactions dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\"" |
NCBI Taxonomy identifier for the host organism | taxid:4932(yeasx) taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") |
Parameters of the interaction | - |
Creation date | 2020/10/05 |
Update date | 2024/11/28 |
negative Boolean value | false |
Feature(s) for interactor A | - |
Feature(s) for interactor B | sufficient binding region:1-159 |
Stoichiometry for interactor A | - |
Stoichiometry for interactor B | - |
Participant identification method for interactor A | Nucleotide sequence identification |
Participant identification method for interactor B | Nucleotide sequence identification |