Curation Details
Interaction ID: IM-28561-955

Unique identifier for interactor Auniprotkb:Q9NRD5
Unique identifier for interactor Buniprotkb:P49815
Alternative identifier for interactor Aintact:EBI-79165
uniprotkb:O95906
intact:EBI-2622151
uniprotkb:B3KS52
ensembl:ENSP00000349465.3
ensembl:ENSP00000385205.3
Alternative identifier for interactor Bintact:EBI-396587
uniprotkb:O75275
uniprotkb:Q8TAZ1
uniprotkb:B4DRN2
uniprotkb:A7E2E2
uniprotkb:B4DIQ7
uniprotkb:Q4LE71
uniprotkb:C9J378
uniprotkb:B4DIL8
uniprotkb:B7Z2B8
ensembl:ENSP00000219476.3
Aliases for Apsi-mi:pick1_human(display_long)
uniprotkb:PICK1(gene name)
psi-mi:PICK1(display_short)
uniprotkb:PRKCABP(gene name synonym)
uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)
uniprotkb:Protein interacting with C kinase 1(gene name synonym)
Aliases for Bpsi-mi:tsc2_human(display_long)
uniprotkb:TSC2(gene name)
psi-mi:TSC2(display_short)
uniprotkb:Tuberous sclerosis 2 protein(gene name synonym)
uniprotkb:TSC4(gene name synonym)
Interaction detection methodspsi-mi:"MI:0398"(two hybrid pooling approach)
First authorSakai et al. (2011)
Identifier of the publicationdoi:10.1126/scitranslmed.3002166
pubmed:21653829
imex:IM-28561
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26516119
imex:IM-28561-955
Confidence scoreintact-miscore:0.51
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST2
comment:"\"Library for Y2H screening used: human brain\""
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn
dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\""
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2020/10/05
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bsufficient binding region:1-410
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification