Curation Details
Interaction ID: IM-28561-787

Unique identifier for interactor Auniprotkb:P23528
Unique identifier for interactor Buniprotkb:O75592
Alternative identifier for interactor Aintact:EBI-352733
uniprotkb:Q53Y87
uniprotkb:Q9UCA2
uniprotkb:B3KUQ1
ensembl:ENSP00000309629.5
ensembl:ENSP00000432660.1
Alternative identifier for interactor Bintact:EBI-1043774
uniprotkb:Q5JSX8
uniprotkb:Q5VZN6
uniprotkb:Q6PIB6
uniprotkb:Q9UQ11
uniprotkb:Q9Y6E4
uniprotkb:A6NJC6
ensembl:ENSP00000444596.2
Aliases for Apsi-mi:cof1_human(display_long)
uniprotkb:CFL1(gene name)
psi-mi:CFL1(display_short)
uniprotkb:CFL(gene name synonym)
uniprotkb:Cofilin, non-muscle isoform(gene name synonym)
uniprotkb:18 kDa phosphoprotein(gene name synonym)
Aliases for Bpsi-mi:mycb2_human(display_long)
uniprotkb:MYCBP2(gene name)
psi-mi:MYCBP2(display_short)
uniprotkb:KIAA0916(gene name synonym)
uniprotkb:PAM(gene name synonym)
uniprotkb:Myc-binding protein 2(gene name synonym)
uniprotkb:Protein associated with Myc(gene name synonym)
Interaction detection methodspsi-mi:"MI:0398"(two hybrid pooling approach)
First authorSakai et al. (2011)
Identifier of the publicationdoi:10.1126/scitranslmed.3002166
pubmed:21653829
imex:IM-28561
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26513051
imex:IM-28561-787
Confidence scoreintact-miscore:0.37
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST2
comment:"\"Library for Y2H screening used: human brain\""
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn
dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\""
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2020/10/05
Update date2024/08/20
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bsufficient binding region:2540-3006
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification