Curation Details
Interaction ID: IM-28561-707

Unique identifier for interactor Auniprotkb:Q17R89
Unique identifier for interactor Buniprotkb:Q9BYB0
Alternative identifier for interactor Aintact:EBI-720416
uniprotkb:A6NCP5
uniprotkb:Q9Y4Q4
uniprotkb:A8MQB2
ensembl:ENSP00000368994.5
uniprotkb:O75160
uniprotkb:Q7Z5Z7
Alternative identifier for interactor Bintact:EBI-1752330
intact:EBI-28969573
uniprotkb:D7UT47
uniprotkb:Q8TET3
Aliases for Apsi-mi:rhg44_human(display_long)
uniprotkb:RhoGAP interacting with CIP4 homologs protein 2(gene name synonym)
uniprotkb:Rho-type GTPase-activating protein RICH2(gene name synonym)
uniprotkb:NPC-A-10(gene name synonym)
uniprotkb:ARHGAP44(gene name)
psi-mi:ARHGAP44(display_short)
uniprotkb:KIAA0672(gene name synonym)
uniprotkb:RICH2(gene name synonym)
Aliases for Bpsi-mi:shan3_human(display_long)
uniprotkb:SHANK3(gene name)
psi-mi:SHANK3(display_short)
uniprotkb:KIAA1650(gene name synonym)
uniprotkb:PSAP2(gene name synonym)
uniprotkb:Proline-rich synapse-associated protein 2(gene name synonym)
uniprotkb:PROSAP2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0398"(two hybrid pooling approach)
First authorSakai et al. (2011)
Identifier of the publicationdoi:10.1126/scitranslmed.3002166
pubmed:21653829
imex:IM-28561
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26514786
imex:IM-28561-707
Confidence scoreintact-miscore:0.37
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST2
comment:"\"Library for Y2H screening used: human brain\""
dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn
dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2020/10/05
Update date2020/12/11
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bsufficient binding region:374-740
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification