Curation Details
Interaction ID: IM-28561-643

Unique identifier for interactor Auniprotkb:Q96CW1
Unique identifier for interactor Buniprotkb:P51114
Alternative identifier for interactor Aintact:EBI-297683
uniprotkb:A6NE12
uniprotkb:P20172
uniprotkb:P53679
uniprotkb:D3DNT1
ensembl:ENSP00000292807.5
Alternative identifier for interactor Bintact:EBI-713291
uniprotkb:A8K9B8
uniprotkb:Q7Z450
uniprotkb:Q8N6R8
ensembl:ENSP00000350170.3
Aliases for Apsi-mi:ap2m1_human(display_long)
uniprotkb:Adaptor protein complex AP-2 subunit mu(gene name synonym)
uniprotkb:AP-2 mu chain(gene name synonym)
uniprotkb:AP2M1(gene name)
psi-mi:AP2M1(display_short)
uniprotkb:CLAPM1(gene name synonym)
uniprotkb:KIAA0109(gene name synonym)
uniprotkb:Adaptin-mu2(gene name synonym)
uniprotkb:Plasma membrane adaptor AP-2 50 kDa protein(gene name synonym)
uniprotkb:HA2 50 kDa subunit(gene name synonym)
uniprotkb:Clathrin coat assembly protein AP50(gene name synonym)
uniprotkb:Clathrin coat-associated protein AP50(gene name synonym)
uniprotkb:Clathrin assembly protein complex 2 mu medium chain(gene name synonym)
uniprotkb:Adaptor-related protein complex 2 subunit mu(gene name synonym)
Aliases for Bpsi-mi:fxr1_human(display_long)
uniprotkb:FXR1(gene name)
psi-mi:FXR1(display_short)
uniprotkb:FMR1 autosomal homolog 1(gene name synonym)
uniprotkb:hFXR1p(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorSakai et al. (2011)
Identifier of the publicationdoi:10.1126/scitranslmed.3002166
pubmed:21653829
imex:IM-28561
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26508401
imex:IM-28561-643
Confidence scoreintact-miscore:0.51
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:SF1
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn
dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\""
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293t)
taxid:9606(Homo sapiens HEK293T embryonic kidney cell)
Parameters of the interaction-
Creation date2020/10/05
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Amyc tag:?-?
Feature(s) for interactor Bglutathione s tranferase tag:?-?
sufficient binding region:215-363
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot