Curation Details
Interaction ID: IM-28561-519

Unique identifier for interactor Auniprotkb:Q8WTU2
Unique identifier for interactor Buniprotkb:P49815
Alternative identifier for interactor Aintact:EBI-20722735
uniprotkb:Q2HIZ5
uniprotkb:Q6ZMG3
uniprotkb:Q96BF5
ensembl:ENSP00000275560.3
Alternative identifier for interactor Bintact:EBI-396587
uniprotkb:O75275
uniprotkb:Q8TAZ1
uniprotkb:B4DRN2
uniprotkb:A7E2E2
uniprotkb:B4DIQ7
uniprotkb:Q4LE71
uniprotkb:C9J378
uniprotkb:B4DIL8
uniprotkb:B7Z2B8
ensembl:ENSP00000219476.3
Aliases for Apsi-mi:srb4d_human(display_long)
uniprotkb:Four scavenger receptor cysteine-rich domains-containing protein(gene name synonym)
uniprotkb:S4D-SRCRB(gene name synonym)
uniprotkb:SSC4D(gene name)
psi-mi:SSC4D(display_short)
uniprotkb:SRCRB4D(gene name synonym)
Aliases for Bpsi-mi:tsc2_human(display_long)
uniprotkb:TSC2(gene name)
psi-mi:TSC2(display_short)
uniprotkb:Tuberous sclerosis 2 protein(gene name synonym)
uniprotkb:TSC4(gene name synonym)
Interaction detection methodspsi-mi:"MI:0398"(two hybrid pooling approach)
First authorSakai et al. (2011)
Identifier of the publicationdoi:10.1126/scitranslmed.3002166
pubmed:21653829
imex:IM-28561
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26516164
imex:IM-28561-519
Confidence scoreintact-miscore:0.37
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST2
comment:"\"Library for Y2H screening used: human brain\""
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn
dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\""
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2020/10/05
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bsufficient binding region:1-410
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification