Curation Details
Interaction ID: IM-28561-297

Unique identifier for interactor Auniprotkb:O94979
Unique identifier for interactor Buniprotkb:Q92574
Alternative identifier for interactor Aintact:EBI-1767898
uniprotkb:Q17RR5
uniprotkb:Q5H9P6
uniprotkb:Q5XG74
uniprotkb:Q659G7
uniprotkb:Q6ZU90
uniprotkb:Q7LCX9
uniprotkb:Q86TJ0
uniprotkb:Q8IZH4
uniprotkb:Q9P048
uniprotkb:Q9P0A6
uniprotkb:Q9UM05
uniprotkb:Q9UM06
ensembl:ENSP00000347329.2
ensembl:ENSP00000378721.2
ensembl:ENSP00000400926.1
uniprotkb:B7ZKZ7
intact:EBI-25605813
uniprotkb:B7ZL00
uniprotkb:B4DIW6
uniprotkb:H7C2W3
Alternative identifier for interactor Bintact:EBI-1047085
uniprotkb:Q5VVN5
intact:EBI-1386638
intact:EBI-28978933
uniprotkb:B7Z897
ensembl:ENSP00000298552.3
ensembl:ENSP00000495158.1
ensembl:ENSP00000495533.2
ensembl:ENSP00000495830.2
ensembl:ENSP00000496263.1
Aliases for Apsi-mi:sc31a_human(display_long)
uniprotkb:SEC31A(gene name)
psi-mi:SEC31A(display_short)
uniprotkb:KIAA0905(gene name synonym)
uniprotkb:SEC31L1(gene name synonym)
uniprotkb:HSPC275(orf name)
uniprotkb:HSPC334(orf name)
uniprotkb:SEC31-related protein A(gene name synonym)
uniprotkb:SEC31-like protein 1(gene name synonym)
uniprotkb:ABP125(gene name synonym)
uniprotkb:ABP130(gene name synonym)
uniprotkb:Web1-like protein(gene name synonym)
Aliases for Bpsi-mi:tsc1_human(display_long)
uniprotkb:TSC1(gene name)
psi-mi:TSC1(display_short)
uniprotkb:KIAA0243(gene name synonym)
uniprotkb:Tuberous sclerosis 1 protein(gene name synonym)
uniprotkb:TSC(gene name synonym)
Interaction detection methodspsi-mi:"MI:0398"(two hybrid pooling approach)
First authorSakai et al. (2011)
Identifier of the publicationdoi:10.1126/scitranslmed.3002166
pubmed:21653829
imex:IM-28561
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26515936
imex:IM-28561-297
Confidence scoreintact-miscore:0.37
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST2
comment:"\"Library for Y2H screening used: human brain\""
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn
dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\""
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2020/10/05
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bsufficient binding region:400-724
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification