Curation Details
Interaction ID: IM-28561-179

Unique identifier for interactor Auniprotkb:Q9NSC5
Unique identifier for interactor Buniprotkb:Q9BYB0
Alternative identifier for interactor Aintact:EBI-748420
intact:EBI-2557809
uniprotkb:E9PCW9
uniprotkb:Q9NSC1
ensembl:ENSP00000376162.2
ensembl:ENSP00000439937.1
ensembl:ENSP00000446026.1
intact:EBI-28972925
intact:EBI-10175777
uniprotkb:B2RA10
uniprotkb:O14580
uniprotkb:O95350
uniprotkb:Q9NSB9
uniprotkb:Q9NSC0
Alternative identifier for interactor Bintact:EBI-1752330
intact:EBI-28969573
uniprotkb:D7UT47
uniprotkb:Q8TET3
Aliases for Apsi-mi:home3_human(display_long)
uniprotkb:HOMER3(gene name)
psi-mi:HOMER3(display_short)
Aliases for Bpsi-mi:shan3_human(display_long)
uniprotkb:SHANK3(gene name)
psi-mi:SHANK3(display_short)
uniprotkb:KIAA1650(gene name synonym)
uniprotkb:PSAP2(gene name synonym)
uniprotkb:Proline-rich synapse-associated protein 2(gene name synonym)
uniprotkb:PROSAP2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0398"(two hybrid pooling approach)
First authorSakai et al. (2011)
Identifier of the publicationdoi:10.1126/scitranslmed.3002166
pubmed:21653829
imex:IM-28561
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26514286
imex:IM-28561-179
Confidence scoreintact-miscore:0.37
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST2
comment:"\"Library for Y2H screening used: human brain\""
dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn
dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2020/10/05
Update date2020/12/11
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bsufficient binding region:1219-1731
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification