Curation Details
Interaction ID: IM-28561-1727

Unique identifier for interactor Auniprotkb:Q6WCQ1
Unique identifier for interactor Buniprotkb:P60484
Alternative identifier for interactor Aintact:EBI-1022605
uniprotkb:Q3KQZ5
uniprotkb:Q5FB94
uniprotkb:Q6DHW2
uniprotkb:Q7Z5Y2
uniprotkb:Q8N390
uniprotkb:Q96G40
ensembl:ENSP00000342379.4
Alternative identifier for interactor Bintact:EBI-696162
uniprotkb:O00633
uniprotkb:O02679
uniprotkb:Q6ICT7
uniprotkb:B2R904
uniprotkb:F2YHV0
ensembl:ENSP00000361021.3
ensembl:ENSP00000494918.2
ensembl:ENSP00000508752.1
ensembl:ENSP00000518242.1
Aliases for Apsi-mi:mprip_human(display_long)
uniprotkb:MRIP(gene name synonym)
uniprotkb:Rho-interacting protein 3(gene name synonym)
uniprotkb:p116Rip(gene name synonym)
uniprotkb:MPRIP(gene name)
psi-mi:MPRIP(display_short)
uniprotkb:KIAA0864(gene name synonym)
uniprotkb:RHOIP3(gene name synonym)
Aliases for Bpsi-mi:pten_human(display_long)
uniprotkb:Phosphatase and tensin homolog(gene name synonym)
uniprotkb:Mutated in multiple advanced cancers 1(gene name synonym)
uniprotkb:PTEN(gene name)
psi-mi:PTEN(display_short)
uniprotkb:MMAC1(gene name synonym)
uniprotkb:TEP1(gene name synonym)
uniprotkb:Inositol polyphosphate 3-phosphatase(gene name synonym)
Interaction detection methodspsi-mi:"MI:0398"(two hybrid pooling approach)
First authorSakai et al. (2011)
Identifier of the publicationdoi:10.1126/scitranslmed.3002166
pubmed:21653829
imex:IM-28561
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26513695
imex:IM-28561-1727
Confidence scoreintact-miscore:0.37
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST2
comment:"\"Library for Y2H screening used: human brain\""
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn
dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\""
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2020/10/05
Update date2020/12/11
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bsufficient binding region:305-403
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification