| Unique identifier for interactor A | uniprotkb:P21333 |
| Unique identifier for interactor B | uniprotkb:P60484 |
| Alternative identifier for interactor A | intact:EBI-350432 uniprotkb:Q8NF52 intact:EBI-1103234 uniprotkb:Q5HY53 uniprotkb:Q5HY55 uniprotkb:E9KL45 ensembl:ENSP00000358866.3 |
| Alternative identifier for interactor B | intact:EBI-696162 uniprotkb:O00633 uniprotkb:O02679 uniprotkb:Q6ICT7 uniprotkb:B2R904 uniprotkb:F2YHV0 ensembl:ENSP00000361021.3 ensembl:ENSP00000494918.2 ensembl:ENSP00000508752.1 ensembl:ENSP00000518242.1 |
| Aliases for A | psi-mi:flna_human(display_long) uniprotkb:FLNA(gene name) psi-mi:FLNA(display_short) uniprotkb:FLN(gene name synonym) uniprotkb:FLN1(gene name synonym) uniprotkb:Alpha-filamin(gene name synonym) uniprotkb:Filamin-1(gene name synonym) uniprotkb:Endothelial actin-binding protein(gene name synonym) uniprotkb:Actin-binding protein 280(gene name synonym) uniprotkb:Non-muscle filamin(gene name synonym) |
| Aliases for B | psi-mi:pten_human(display_long) uniprotkb:Phosphatase and tensin homolog(gene name synonym) uniprotkb:Mutated in multiple advanced cancers 1(gene name synonym) uniprotkb:PTEN(gene name) psi-mi:PTEN(display_short) uniprotkb:MMAC1(gene name synonym) uniprotkb:TEP1(gene name synonym) uniprotkb:Inositol polyphosphate 3-phosphatase(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0398"(two hybrid pooling approach) |
| First author | Sakai et al. (2011) |
| Identifier of the publication | doi:10.1126/scitranslmed.3002166 pubmed:21653829 imex:IM-28561 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-26513686 imex:IM-28561-1725 |
| Confidence score | intact-miscore:0.37 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:ST2 comment:"\"Library for Y2H screening used: human brain\"" curation depth:imex curation full coverage:Only protein-protein interactions dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\"" |
| NCBI Taxonomy identifier for the host organism | taxid:4932(yeasx) taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") |
| Parameters of the interaction | - |
| Creation date | 2020/10/05 |
| Update date | 2024/08/20 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | sufficient binding region:305-403 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Nucleotide sequence identification |
| Participant identification method for interactor B | Nucleotide sequence identification |