Curation Details
Interaction ID: IM-28561-1513

Unique identifier for interactor Auniprotkb:Q9UBP4
Unique identifier for interactor Buniprotkb:Q7Z417
Alternative identifier for interactor Aintact:EBI-954409
uniprotkb:Q9ULB7
uniprotkb:A8K1I2
uniprotkb:D3DQW1
ensembl:ENSP00000314910.4
ensembl:ENSP00000379762.2
ensembl:ENSP00000506835.1
Alternative identifier for interactor Bintact:EBI-1210753
intact:EBI-10172018
uniprotkb:A1L3A7
uniprotkb:Q9P2M5
uniprotkb:A1L3A6
ensembl:ENSP00000225388.3
Aliases for Apsi-mi:dkk3_human(display_long)
uniprotkb:REIC(gene name synonym)
uniprotkb:UNQ258/PRO295(orf name)
uniprotkb:DKK3(gene name)
psi-mi:DKK3(display_short)
Aliases for Bpsi-mi:nufp2_human(display_long)
uniprotkb:NUFIP2(gene name)
psi-mi:NUFIP2(display_short)
uniprotkb:KIAA1321(gene name synonym)
uniprotkb:FMRP-interacting protein 2(gene name synonym)
uniprotkb:82 kDa FMRP-interacting protein(gene name synonym)
uniprotkb:Cell proliferation-inducing gene 1 protein(gene name synonym)
uniprotkb:Nuclear FMR1-interacting protein 2(gene name synonym)
uniprotkb:PIG1(orf name)
Interaction detection methodspsi-mi:"MI:0398"(two hybrid pooling approach)
First authorSakai et al. (2011)
Identifier of the publicationdoi:10.1126/scitranslmed.3002166
pubmed:21653829
imex:IM-28561
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26513398
imex:IM-28561-1513
Confidence scoreintact-miscore:0.37
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST2
comment:"\"Library for Y2H screening used: human brain\""
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn
dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\""
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2020/10/05
Update date2024/08/20
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bsufficient binding region:1-340
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification