| Unique identifier for interactor A | uniprotkb:P12814 |
| Unique identifier for interactor B | uniprotkb:Q92574 |
| Alternative identifier for interactor A | intact:EBI-351710 uniprotkb:Q9BTN1 uniprotkb:Q1HE25 uniprotkb:B7TY16 intact:EBI-3866221 uniprotkb:B3V8S3 uniprotkb:B4DHH3 ensembl:ENSP00000193403.6 |
| Alternative identifier for interactor B | intact:EBI-1047085 uniprotkb:Q5VVN5 intact:EBI-1386638 intact:EBI-28978933 uniprotkb:B7Z897 ensembl:ENSP00000298552.3 ensembl:ENSP00000495158.1 ensembl:ENSP00000495533.2 ensembl:ENSP00000495830.2 ensembl:ENSP00000496263.1 |
| Aliases for A | psi-mi:actn1_human(display_long) uniprotkb:ACTN1(gene name) psi-mi:ACTN1(display_short) uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym) uniprotkb:Non-muscle alpha-actinin-1(gene name synonym) uniprotkb:F-actin cross-linking protein(gene name synonym) |
| Aliases for B | psi-mi:tsc1_human(display_long) uniprotkb:TSC1(gene name) psi-mi:TSC1(display_short) uniprotkb:KIAA0243(gene name synonym) uniprotkb:Tuberous sclerosis 1 protein(gene name synonym) uniprotkb:TSC(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0398"(two hybrid pooling approach) |
| First author | Sakai et al. (2011) |
| Identifier of the publication | doi:10.1126/scitranslmed.3002166 pubmed:21653829 imex:IM-28561 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-26515395 imex:IM-28561-1413 |
| Confidence score | intact-miscore:0.37 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:ST2 comment:"\"Library for Y2H screening used: human brain\"" curation depth:imex curation full coverage:Only protein-protein interactions dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\"" |
| NCBI Taxonomy identifier for the host organism | taxid:4932(yeasx) taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") |
| Parameters of the interaction | - |
| Creation date | 2020/10/05 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | sufficient binding region:720-1000 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Nucleotide sequence identification |
| Participant identification method for interactor B | Nucleotide sequence identification |