Curation Details
Interaction ID: IM-28561-1391

Unique identifier for interactor Auniprotkb:Q59EK9
Unique identifier for interactor Buniprotkb:Q9BYB0
Alternative identifier for interactor Aintact:EBI-747225
uniprotkb:B2R974
uniprotkb:O15483
uniprotkb:Q7Z3S2
uniprotkb:Q9UF50
intact:EBI-949746
uniprotkb:O60651
ensembl:ENSP00000410862.2
Alternative identifier for interactor Bintact:EBI-1752330
uniprotkb:D7UT47
uniprotkb:Q8TET3
intact:EBI-28969573
Aliases for Apsi-mi:run3a_human(display_long)
uniprotkb:RUNDC3A(gene name)
psi-mi:RUNDC3A(display_short)
uniprotkb:RAP2IP(gene name synonym)
uniprotkb:RPIP8(gene name synonym)
uniprotkb:Rap2-interacting protein 8(gene name synonym)
Aliases for Bpsi-mi:shan3_human(display_long)
uniprotkb:SHANK3(gene name)
psi-mi:SHANK3(display_short)
uniprotkb:KIAA1650(gene name synonym)
uniprotkb:PSAP2(gene name synonym)
uniprotkb:Proline-rich synapse-associated protein 2(gene name synonym)
uniprotkb:PROSAP2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0398"(two hybrid pooling approach)
First authorSakai et al. (2011)
Identifier of the publicationdoi:10.1126/scitranslmed.3002166
pubmed:21653829
imex:IM-28561
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26514822
imex:IM-28561-1391
Confidence scoreintact-miscore:0.37
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST2
comment:"\"Library for Y2H screening used: human brain\""
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn
dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\""
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2020/10/05
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bsufficient binding region:374-740
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification