Curation Details
Interaction ID: IM-28561-1245

Unique identifier for interactor Auniprotkb:P31749
Unique identifier for interactor Buniprotkb:Q9NZ94
Alternative identifier for interactor Aintact:EBI-296087
uniprotkb:Q9BWB6
uniprotkb:B2RAM5
ensembl:ENSP00000270202.4
ensembl:ENSP00000384293.2
ensembl:ENSP00000385326.2
ensembl:ENSP00000450688.1
ensembl:ENSP00000451166.1
ensembl:ENSP00000451828.1
ensembl:ENSP00000497822.1
ensembl:ENSP00000507879.1
uniprotkb:B7Z5R1
Alternative identifier for interactor Bintact:EBI-3920184
uniprotkb:Q9NZ95
uniprotkb:Q9NZ96
uniprotkb:D3DVV0
uniprotkb:Q9NZ97
uniprotkb:Q9P248
uniprotkb:Q8NCD0
uniprotkb:D3DVV1
uniprotkb:B2RBK1
uniprotkb:D2X2H6
uniprotkb:Q86V51
ensembl:ENSP00000351591.4
Aliases for Apsi-mi:akt1_human(display_long)
uniprotkb:AKT1(gene name)
psi-mi:AKT1(display_short)
uniprotkb:PKB(gene name synonym)
uniprotkb:RAC(gene name synonym)
uniprotkb:RAC-PK-alpha(gene name synonym)
uniprotkb:Protein kinase B(gene name synonym)
uniprotkb:Proto-oncogene c-Akt(gene name synonym)
uniprotkb:Protein kinase B alpha(gene name synonym)
Aliases for Bpsi-mi:nlgn3_human(display_long)
uniprotkb:NLGN3(gene name)
psi-mi:NLGN3(display_short)
uniprotkb:KIAA1480(gene name synonym)
uniprotkb:NL3(gene name synonym)
uniprotkb:Gliotactin homolog(gene name synonym)
Interaction detection methodspsi-mi:"MI:0398"(two hybrid pooling approach)
First authorSakai et al. (2011)
Identifier of the publicationdoi:10.1126/scitranslmed.3002166
pubmed:21653829
imex:IM-28561
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26513290
imex:IM-28561-1245
Confidence scoreintact-miscore:0.37
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST2
comment:"\"Library for Y2H screening used: human brain\""
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn
dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\""
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2020/10/05
Update date2020/12/11
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bsufficient binding region:712-848
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification