Curation Details
Interaction ID: IM-28561-1223

Unique identifier for interactor Auniprotkb:Q99750
Unique identifier for interactor Buniprotkb:Q9UIS9
Alternative identifier for interactor Aintact:EBI-724076
ensembl:ENSP00000230321.6
ensembl:ENSP00000362142.2
Alternative identifier for interactor Bintact:EBI-867196
uniprotkb:K7ELI2
uniprotkb:Q9UNZ9
uniprotkb:K7EQZ4
uniprotkb:K7ESN0
uniprotkb:A4UTZ0
uniprotkb:O15248
uniprotkb:O95241
uniprotkb:Q7Z7B5
uniprotkb:Q8N4W4
uniprotkb:Q9UNZ6
uniprotkb:Q9UNZ7
uniprotkb:Q9UNZ8
uniprotkb:B4DXJ5
uniprotkb:E9PEC5
intact:EBI-10977266
ensembl:ENSP00000269468.5
ensembl:ENSP00000372407.5
ensembl:ENSP00000467017.1
Aliases for Apsi-mi:mdfi_human(display_long)
uniprotkb:Myogenic repressor I-mf(gene name synonym)
uniprotkb:MDFI(gene name)
psi-mi:MDFI(display_short)
Aliases for Bpsi-mi:mbd1_human(display_long)
uniprotkb:CXXC3(gene name synonym)
uniprotkb:Methyl-CpG-binding protein MBD1(gene name synonym)
uniprotkb:Protein containing methyl-CpG-binding domain 1(gene name synonym)
uniprotkb:CXXC-type zinc finger protein 3(gene name synonym)
uniprotkb:MBD1(gene name)
psi-mi:MBD1(display_short)
uniprotkb:PCM1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0398"(two hybrid pooling approach)
First authorSakai et al. (2011)
Identifier of the publicationdoi:10.1126/scitranslmed.3002166
pubmed:21653829
imex:IM-28561
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26512866
imex:IM-28561-1223
Confidence scoreintact-miscore:0.37
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST2
comment:"\"Library for Y2H screening used: human brain\""
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn
dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\""
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2020/10/05
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bsufficient binding region:80-340
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification