Curation Details
Interaction ID: IM-28561-1179

Unique identifier for interactor Auniprotkb:P53779
Unique identifier for interactor Buniprotkb:Q05086
Alternative identifier for interactor Aintact:EBI-713543
uniprotkb:A6NFS3
uniprotkb:Q15707
uniprotkb:Q49AP1
uniprotkb:A6NG28
uniprotkb:B3KQ94
ensembl:ENSP00000424154.3
ensembl:ENSP00000492204.1
ensembl:ENSP00000492292.1
ensembl:ENSP00000492903.1
ensembl:ENSP00000493013.1
ensembl:ENSP00000493045.1
ensembl:ENSP00000493072.1
ensembl:ENSP00000493275.1
ensembl:ENSP00000493290.1
ensembl:ENSP00000493363.1
ensembl:ENSP00000493375.1
ensembl:ENSP00000493408.1
ensembl:ENSP00000493435.1
ensembl:ENSP00000493450.1
Alternative identifier for interactor Bintact:EBI-954357
uniprotkb:P78355
uniprotkb:Q93066
uniprotkb:Q9UEP4
uniprotkb:Q9UEP5
uniprotkb:Q9UEP6
uniprotkb:Q9UEP7
uniprotkb:Q9UEP8
uniprotkb:Q9UEP9
uniprotkb:A8K8Z9
ensembl:ENSP00000497594.1
Aliases for Apsi-mi:mk10_human(display_long)
uniprotkb:Stress-activated protein kinase JNK3(gene name synonym)
uniprotkb:c-Jun N-terminal kinase 3(gene name synonym)
uniprotkb:MAP kinase p49 3F12(gene name synonym)
uniprotkb:MAPK10(gene name)
psi-mi:MAPK10(display_short)
uniprotkb:JNK3(gene name synonym)
uniprotkb:JNK3A(gene name synonym)
uniprotkb:PRKM10(gene name synonym)
uniprotkb:Stress-activated protein kinase 1b(gene name synonym)
uniprotkb:SAPK1B(gene name synonym)
Aliases for Bpsi-mi:ube3a_human(display_long)
uniprotkb:E6AP ubiquitin-protein ligase(gene name synonym)
uniprotkb:Oncogenic protein-associated protein E6-AP(gene name synonym)
uniprotkb:Human papillomavirus E6-associated protein(gene name synonym)
uniprotkb:Renal carcinoma antigen NY-REN-54(gene name synonym)
uniprotkb:UBE3A(gene name)
psi-mi:UBE3A(display_short)
uniprotkb:E6AP(gene name synonym)
uniprotkb:EPVE6AP(gene name synonym)
uniprotkb:HPVE6A(gene name synonym)
uniprotkb:HECT-type ubiquitin transferase E3A(gene name synonym)
Interaction detection methodspsi-mi:"MI:0398"(two hybrid pooling approach)
First authorSakai et al. (2011)
Identifier of the publicationdoi:10.1126/scitranslmed.3002166
pubmed:21653829
imex:IM-28561
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26516200
imex:IM-28561-1179
Confidence scoreintact-miscore:0.37
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST2
comment:"\"Library for Y2H screening used: human brain\""
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn
dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\""
NCBI Taxonomy identifier for the host organismtaxid:4932(yeasx)
taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")
Parameters of the interaction-
Creation date2020/10/05
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification